Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+
about
Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinolCharacterization of key residues and membrane association domains in retinol dehydrogenase 10The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersCrystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovosePharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid DehydrogenasesThe structural biology of oestrogen metabolismInsights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigationPorcine carbonyl reductase. structural basis for a functional monomer in short chain dehydrogenases/reductasesCofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientationBinary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapyAn intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activityHydroxybenzothiazoles as new nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1)Differences in catalytic activity between rat testicular and ovarian carbonyl reductases are due to two amino acidsDetecting clusters of mutationsAromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: structure-function studies and inhibitor development.Functional mechanism of C-terminal tail in the enzymatic role of porcine testicular carbonyl reductase: a combined experiment and molecular dynamics simulation study of the C-terminal tail in the enzymatic role of PTCR.Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration.Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer.Structure of Equilenin at 100 K: an estrone-related steroid.Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation.Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.Comparative investigation of the in vitro inhibitory potencies of 13-epimeric estrones and D-secoestrones towards 17β-hydroxysteroid dehydrogenase type 1.Design and synthesis of substrate mimetics based on an indole scaffold: potential inhibitors of 17β-HSD type 1.Engineering of 3-ketosteroid-∆-dehydrogenase based site-directed saturation mutagenesis for efficient biotransformation of steroidal substrates
P2860
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P2860
Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@ast
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@en
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@nl
type
label
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@ast
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@en
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@nl
prefLabel
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@ast
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@en
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@nl
P2093
P2860
P356
P1476
Structure of the ternary compl ...... aen-17-one (equilin) and NADP+
@en
P2093
P2860
P356
10.1073/PNAS.96.3.840
P407
P577
1999-02-02T00:00:00Z