The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 - Wikidata - wikimedia - TriplyDB

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

http://www.wikidata.org/entity/Q24684014

about

Nosema ceranae escapes fumagillin control in honey bees Epolactaene binds human Hsp60 Cys442 resulting in the inhibition of chaperone activity Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms Effect of nitroxoline on angiogenesis and growth of human bladder cancer The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase An orally delivered small-molecule formulation with antiangiogenic and anticancer activity Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2 Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay The Development of Genetic Modification Techniques in Intracellular Parasites and Potential Applications to Microsporidia Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity From epoxomicin to carfilzomib: chemistry, biology, and medical outcomes N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects Ubiquitin-mediated response to microsporidia and virus infection in C. elegans Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes Heterologous expression and purification of Vibrio proteolyticus (Aeromonas proteolytica) aminopeptidase: A rapid protocol Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470 Structural Analysis of Bengamide Derivatives as Inhibitors of Methionine Aminopeptidases Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1 Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 in Cells Therapeutic strategies for human microsporidia infections Chemogenomics: an emerging strategy for rapid target and drug discovery Syntheses of fumagillin and ovalicin Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents Pulmonary Hypertension in monocrotaline-injured rats Advances in Bacterial Methionine Aminopeptidase Inhibition Obesity: Current and potential pharmacotherapeutics and targets.Perfluorocarbon nanoparticles: evolution of a multimodality and multifunctional imaging agent.Theragnostics for tumor and plaque angiogenesis with perfluorocarbon nanoemulsions Nanomedicine strategies for molecular targets with MRI and optical imaging.Identification of arsenic-binding proteins in human breast cancer cells Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes Chemical genetics for therapeutic target mining.Chemical genetics: ligand-based discovery of gene function.

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The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

http://www.wikidata.org/entity/Q24684014

description

1997 nî lūn-bûn

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1997 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1997 թվականի հունիսին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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Proceedings of the National Academy of Sciences of the United States of America

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The anti-angiogenic agent fuma ...... ionine aminopeptidase, MetAP-2

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C M Crews

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J J Wen

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L Meng

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M Q Wang

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N Sin

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W G Bornmann

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P2860

Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes

Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases.

Characteristics of the eukaryotic initiation factor 2 associated 67-kDa polypeptide

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

In vivo half-life of a protein is a function of its amino-terminal residue

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

Roles of a 67-kDa polypeptide in reversal of protein synthesis inhibition in heme-deficient reticulocyte lysate.

Molecular cloning of a human complementary DNA encoding an initiation factor 2-associated protein (p67).

A eukaryotic translation initiation factor 2-associated 67 kDa glycoprotein partially reverses protein synthesis inhibition by activated double-stranded RNA-dependent protein kinase in intact cells.

Inhibition of angiogenesis.

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6099-103

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12

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