A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria
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Plant D-2-hydroxyglutarate dehydrogenase participates in the catabolism of lysine especially during senescenceBiosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1The effect of hinge mutations on effector binding and domain rotation in Escherichia coli D-3-phosphoglycerate dehydrogenaseCrystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysineSer3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae.Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.Cloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenaseD-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberculosis is a link between the Escherichia coli and mammalian enzymesDiscovery of novel allosteric effectors based on the predicted allosteric sites for Escherichia coli D-3-phosphoglycerate dehydrogenaseSpecific interactions at the regulatory domain-substrate binding domain interface influence the cooperativity of inhibition and effector binding in Escherichia coli D-3-phosphoglycerate dehydrogenase.Transient kinetic analysis of the interaction of L-serine with Escherichia coli D-3-phosphoglycerate dehydrogenase reveals the mechanism of V-type regulation and the order of effector bindingNovel regulatory mechanism of serine biosynthesis associated with 3-phosphoglycerate dehydrogenase in Arabidopsis thaliana.The contribution of adjacent subunits to the active sites of D-3-phosphoglycerate dehydrogenase.Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis.Contrasting catalytic and allosteric mechanisms for phosphoglycerate dehydrogenases.Quantitative relationships of site to site interaction in Escherichia coli D-3-phosphoglycerate dehydrogenase revealed by asymmetric hybrid tetramers.Metabolite proofreading, a neglected aspect of intermediary metabolism.A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor.Transient kinetic analysis of L-serine interaction with Escherichia coli D-3-phosphoglycerate dehydrogenase containing amino acid mutations in the hinge regions.An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.Molecular, genetic, and biochemical characterization of the serC gene of Methanosarcina barkeri FusaroMaximization of transcription of the serC (pdxF)-aroA multifunctional operon by antagonistic effects of the cyclic AMP (cAMP) receptor protein-cAMP complex and Lrp global regulators of Escherichia coli K-12.Pseudomonas aeruginosa serA Gene Is Required for Bacterial Translocation through Caco-2 Cell Monolayers.The relationship between effector binding and inhibition of activity in D-3-phosphoglycerate dehydrogenase.Identification of Escherichia coli YgaF as an L-2-hydroxyglutarate oxidase.The importance of serine metabolism in cancerDirected evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase.Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate.α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibitionA stopped flow transient kinetic analysis of substrate binding and catalysis in Escherichia coli D-3-phosphoglycerate dehydrogenase.D-2-Hydroxyglutaric aciduria: biochemical marker or clinical disease entity?Multiple turnovers of the nicotino-enzyme PdxB require α-keto acids as cosubstratesMetabolic pathway of α-ketoglutarate in Lactobacillus sanfranciscensis and Lactobacillus reuteri during sourdough fermentation.Amino acid residue mutations uncouple cooperative effects in Escherichia coli D-3-phosphoglycerate dehydrogenase.Structure of the Lrp-regulated serA promoter of Escherichia coli K-12.Cofactor binding to Escherichia coli D-3-phosphoglycerate dehydrogenase induces multiple conformations which alter effector binding.De-regulation of D-3-phosphoglycerate dehydrogenase by domain removal.Hybrid tetramers reveal elements of cooperativity in Escherichia coli D-3-phosphoglycerate dehydrogenase.Molecular and biochemical characterization of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways.The genetic basis for the adaptation of E. coli to sugar synthesis from CO2.
P2860
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P2860
A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@ast
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@en
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@nl
type
label
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@ast
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@en
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@nl
prefLabel
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@ast
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@en
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@nl
P2860
P3181
P1476
A novel alpha-ketoglutarate re ...... man 2-hydroxyglutaric aciduria
@en
P2093
P2860
P3181
P356
10.1128/JB.178.1.232-239.1996
P407
P577
1996-01-01T00:00:00Z