Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
about
Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cellsA novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrestRegulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1)PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1bFocal adhesions regulate Abeta signaling and cell death in Alzheimer's diseaseTransforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancerTargeting CDK4 and CDK6: From Discovery to TherapyFunction and regulation of cullin-RING ubiquitin ligasesPhosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformationPERK mediates cell-cycle exit during the mammalian unfolded protein responseIkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylationCyclins: roles in mitogenic signaling and oncogenic transformationGlycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localizationThe ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transitionp21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cellsCooperation of DLC1 and CDK6 affects breast cancer clinical outcomeMAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomasSchlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinaseActivation of p42 mitogen-activated protein kinase (MAPK), but not c-Jun NH(2)-terminal kinase, induces phosphorylation and stabilization of MAPK phosphatase XCL100 in Xenopus oocytesHyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitroUbiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formationCyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesisBRAF mutation predicts sensitivity to MEK inhibitionMyc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalizationDisruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesisInhibition of human breast cancer cell growth by blockade of the mevalonate-protein prenylation pathway is not prevented by overexpression of cyclin D1.A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells.p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers.Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.Leishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage.Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2aForkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886)Nuclear accumulation of cyclin D1 following long-term fractionated exposures to low-dose ionizing radiation in normal human diploid cells.Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1.Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
P2860
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P2860
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@ast
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@en
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@nl
type
label
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@ast
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@en
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@nl
prefLabel
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@ast
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@en
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@nl
P2093
P2860
P356
P1476
Assembly of cyclin D-dependent ...... d protein kinase kinase (MEK1)
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.3.1091
P407
P577
1998-02-01T00:00:00Z