In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
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Urinary excretion and bactericidal activities of a single oral dose of 400 milligrams of fleroxacin versus a single oral dose of 800 milligrams of pefloxacin in healthy volunteersAntimicrobial activity of Ro 23-9424, a novel ester-linked codrug of fleroxacin and desacetylcefotaxime.Activity of fleroxacin alone and in combination with clindamycin or metronidazole in experimental intra-abdominal abscessesEffect of a fat- and calcium-rich breakfast on pharmacokinetics of fleroxacin administered in single and multiple doses.Antibacterial activities and pharmacokinetics of E-4767 and E-5065, two new 8-chlorofluoroquinolones with a 7-azetidin ring substituent.Ofloxacin: its pharmacology, pharmacokinetics, and potential for clinical application.E-4695, a new C-7 azetidinyl fluoronaphthyridine with enhanced activity against gram-positive and anaerobic pathogens.Pharmacokinetics and metabolism of intravenous and oral fleroxacin in subjects with normal and impaired renal function and in patients on continuous ambulatory peritoneal dialysis.Renal handling of fleroxacin in rabbits, dogs, and humans.Multiple-dose pharmacokinetics of ofloxacin in serum, saliva, and skin blister fluid of healthy volunteersIn vitro activity of Ro 23-9424, a dual-action cephalosporin, compared with activities of other antibiotics.In vitro evaluation of WIN 57273, a new broad-spectrum fluoroquinolone.Double-blind, dose-range-finding study of fleroxacin (RO 23-6240; AM-833) for treatment of complicated urinary tract infections.Comparative in vitro activity of a new quinolone, fleroxacin, against respiratory pathogens from patients with cystic fibrosis.In vitro susceptibilities of Pseudomonas pseudomallei to 27 antimicrobial agents.Comparative in vitro and in vivo activities of six new monofluoroquinolone and difluoroquinolone 3-carboxylic acids with a 7-azetidin ring substituent.Pharmacokinetics and biliary concentrations of fleroxacin in cholecystectomized patientsTreatment of experimental Salmonella typhimurium infection in mice with fleroxacinIn vitro and in vivo activities of QA-241, a new tricyclic quinolone derivativeFleroxacin (Ro 23-6240) distribution in canine prostatic tissue and fluids.In vitro and in vivo antibacterial activities of E-4868, a new fluoroquinolone with a 7-azetidin ring substituent.The pharmacokinetics of oral fleroxacin and ciprofloxacin in plasma and sputum during acute and chronic dosingDevelopment of resistance to fleroxacin during therapy of experimental methicillin-susceptible Staphylococcus aureus endocarditisSusceptibility of Staphylococcus species and subspecies to fleroxacinPenetration of moxifloxacin into bone evaluated by Monte Carlo simulation.Impermeability to quinolones in gram-positive and gram-negative bacteria.A review of the antimicrobial activity of the fluoroquinolones.Quinolone antimicrobial agents: adverse effects and bacterial resistance.Structure-activity relationships of the fluoroquinolones.Developments in quinolones. Bacteriology, pharmacokinetics and initial clinical experience of several investigational quinolone derivatives.Ciprofloxacin: chemistry, mechanism of action, resistance, antimicrobial spectrum, pharmacokinetics, clinical trials, and adverse reactions.The 4-quinolone antibiotics: past, present, and future.Mode of action, and in vitro and in vivo activities of the fluoroquinolones.In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents.In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones.Comparative in vitro activity of a new fluorinated 4-quinolone, T-3262 (A-60969).DNA gyrase of Staphylococcus aureus and inhibitory effect of quinolones on its activity.Efficacy of fleroxacin in experimental methicillin-resistant Staphylococcus aureus endocarditis.Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans.Fleroxacin pharmacokinetics in patients with liver cirrhosis
P2860
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P2860
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
description
1986 nî lūn-bûn
@nan
1986 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@ast
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@en
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@nl
type
label
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@ast
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@en
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@nl
prefLabel
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@ast
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@en
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@nl
P2093
P2860
P356
P1476
In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone
@en
P2093
P2860
P304
P356
10.1128/AAC.29.4.675
P407
P577
1986-04-01T00:00:00Z