Knockout of ERK5 causes multiple defects in placental and embryonic development
about
Conditional deletion of ERK5 MAP kinase in the nervous system impairs pheromone information processing and pheromone-evoked behaviorsLaminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activationErk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesX-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific InhibitorERK5 Mediated Signalling in Diabetic RetinopathyMitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathwayMammalian Llgl2 is necessary for proper branching morphogenesis during placental developmentIntegration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell IdentityCanonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complexExtracellular Signal-Regulated Kinase 5 is Required for Low-Concentration H2O2-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells.Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate.Molecular profiles of mitogen activated protein kinase signaling pathways in orofacial development.ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells.Lipopolysaccharide induces cytokine production and decreases extravillous trophoblast invasion through a mitogen-activated protein kinase-mediated pathway: possible mechanisms of first trimester placental dysfunctionp90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants.Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct ExpansionDevelopment of structures and transport functions in the mouse placenta.MAPK signalling: ERK5 versus ERK1/2.MKK signaling and vascularization.Erk5 contributes to maintaining the balance of cellular nucleotide levels and erythropoiesis.Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.Role of mitogen-activated protein kinase kinase kinases in signal integration.MAP kinases and the control of nuclear events.ERK5 kinase activity is dispensable for cellular immune response and proliferation.Role of extracellular signal-regulated kinase 5 in adipocyte signaling.MEKK2 regulates focal adhesion stability and motility in invasive breast cancer cells.Absence of ERK5/MAPK7 delays tumorigenesis in Atm-/- mice.Mechanotransduction: a major regulator of homeostasis and development.The role of ERK5 in endothelial cell function.Cell Signaling Pathways Involved During Invasion and Syncytialization of Trophoblast Cells.The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma.Cyclic fluid shear stress promotes osteoblastic cells proliferation through ERK5 signaling pathway.A novel mitogen-activated protein kinase docking site in the N terminus of MEK5alpha organizes the components of the extracellular signal-regulated kinase 5 signaling pathway.MEK5 and ERK5 are mediators of the pro-myogenic actions of IGF-2.Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.
P2860
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P2860
Knockout of ERK5 causes multiple defects in placental and embryonic development
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Knockout of ERK5 causes multiple defects in placental and embryonic development
@ast
Knockout of ERK5 causes multiple defects in placental and embryonic development
@en
Knockout of ERK5 causes multiple defects in placental and embryonic development
@nl
type
label
Knockout of ERK5 causes multiple defects in placental and embryonic development
@ast
Knockout of ERK5 causes multiple defects in placental and embryonic development
@en
Knockout of ERK5 causes multiple defects in placental and embryonic development
@nl
prefLabel
Knockout of ERK5 causes multiple defects in placental and embryonic development
@ast
Knockout of ERK5 causes multiple defects in placental and embryonic development
@en
Knockout of ERK5 causes multiple defects in placental and embryonic development
@nl
P2093
P2860
P3181
P356
P1476
Knockout of ERK5 causes multiple defects in placental and embryonic development
@en
P2093
Calum Thompson
J Simon C Arthur
Julia Carr
Peter R Ashby
Victoria Murry-Tait
P2860
P2888
P3181
P356
10.1186/1471-213X-3-11
P407
P577
2003-12-16T00:00:00Z
P5875
P6179
1008372752