Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
about
Cytochromes P450 and experimental models of drug metabolism.A role for solvents in the toxicity of agricultural organophosphorus pesticides.Use of nontraditional animals for evaluation of pharmaceutical products.Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin.Animal models of toxicology testing: the role of pigs.Experimental hepatocyte xenotransplantation--a comprehensive review of the literature.Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway.IFN-γ regulates cytochrome 3A29 through pregnane X receptor in pigs.In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs.Comparison of the substrate kinetics of pig CYP3A29 with pig liver microsomes and human CYP3A4.Is Science the Only Driver in Species Selection? An Internal Study to Evaluate Compound Requirements in the Minipig Compared to the Dog in Preclinical Studies.Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2.Pigs in Toxicology: Breed Differences in Metabolism and Background Findings.Model systems based on experimental animals for studies on drug metabolism in man: (mini)pig cytochromes P450 3A29 and 2E1.Ontogeny of CYP3A and P-glycoprotein in the liver and the small intestine of the Göttingen minipig: an immunohistochemical evaluation.Extensive intestinal glucuronidation of raloxifene in vivo in pigs and impact for oral drug delivery.Metabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases.Cannabidiol Does Not Convert to Δ9-Tetrahydrocannabinol in an In Vivo Animal Model.Tissue distribution of CYP3A29 mRNA expression in Bama miniature pig by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR).Assessment of the effect of grape seed cake inclusion in the diet of healthy fattening-finishing pigs.The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine.Age-related Differences in CYP3A Abundance and Activity in the Liver of the Göttingen Minipig.Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
P2860
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P2860
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
description
2001 nî lūn-bûn
@nan
2001 թուականին հրատարակուած գիտական յօդուած
@hyw
2001 թվականին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@ast
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@en
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@nl
type
label
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@ast
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@en
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@nl
prefLabel
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@ast
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@en
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@nl
P2093
P2860
P3181
P356
P1433
P1476
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
@en
P2093
F P Guengerich
P Anzenbacher
P2860
P2888
P3181
P356
10.1186/1471-2210-1-11
P407
P577
2001-01-01T00:00:00Z
P5875
P6179
1029583561