Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
about
The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based studyTamoxifen Resistance: Emerging Molecular TargetsBRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cellsEstrogen receptor mutations and changes in downstream gene expression and signalingGrowth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305.Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ERalpha transgenic mice.Absence of the K303R estrogen receptor α mutation in breast cancer patients exhibiting different responses to aromatase inhibitor anastrozole neoadjuvant treatment.Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients.ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer.Epigenetics meets estrogen receptor: regulation of estrogen receptor by direct lysine methylation.
P2860
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P2860
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@ast
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@en
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@nl
type
label
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@ast
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@en
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@nl
prefLabel
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@ast
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@en
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@nl
P2093
P2860
P3181
P356
P1476
Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas
@en
P2093
D Ross Sibson
Helen Innes
Michael P A Davies
Penny A O'Neill
P2860
P2888
P304
P3181
P356
10.1186/BCR965
P407
P577
2004-11-23T00:00:00Z
P5875
P6179
1047608505