Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice
about
Mouse models of human autoimmune diseases: essential tools that require the proper controlsLinking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusInsufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout miceCD22: an inhibitory enigmaMndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibilityPentraxins: structure, function, and role in inflammationAmelioration of lupus nephritis by serum amyloid P component gene therapy with distinct mechanisms varied from different stage of the disease.Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae.Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a.SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsC1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRIAltered B cell signalling in autoimmunity.NETs: the missing link between cell death and systemic autoimmune diseases?Dichotomy in FcγRIIB deficiency and autoimmune-prone SLAM haplotype clarifies the roles of the Fc receptor in development of autoantibodies and glomerulonephritis.Long-term treatment of NZB mice with anti-CD4 results in wasting disease, lymphoid atrophy and chronic diarrhea.All (C57BL/6) Mice are not Created Equal.Uncoupling of natural IgE production and CD23 surface expression levelsDistinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production.The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosusGenetic background can result in a marked or minimal effect of gene knockout (GPR55 and CB2 receptor) in experimental autoimmune encephalomyelitis models of multiple sclerosis.Cutting edge: an NK cell-independent role for Slamf4 in controlling humoral autoimmunity.A novel isoform of the Ly108 gene ameliorates murine lupus.Persistent lung inflammation and fibrosis in serum amyloid P component (APCs-/-) knockout miceLack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammationB cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance.The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production.IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lpr miceThe candidate gene approach: have murine models informed the study of human SLE?Amyloid-DNA Composites of Bacterial Biofilms Stimulate AutoimmunityB cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.FcγRIIb and BAFF differentially regulate peritoneal B1 cell survival.Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity.Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response.Analyzing pathogenic (double-stranded (ds) DNA-specific) plasma cells via immunofluorescence microscopy.Analysis of C4 and the C4 binding protein in the MRL/lpr mouseAnalysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.Complement deficiencies in humans and animals: links to autoimmunity.Quorum sensing contributes to activated IgM-secreting B cell homeostasis.Regulation of allograft survival by inhibitory FcγRIIb signaling
P2860
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P2860
Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@ast
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@en
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@nl
type
label
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@ast
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@en
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@nl
altLabel
Spontaneous Autoimmunity in 12 ...... escribed in Gene-Targeted Mice
@en
prefLabel
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@ast
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@en
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@nl
P2093
P2860
P50
P3181
P1433
P1476
Spontaneous autoimmunity in 12 ...... escribed in gene-targeted mice
@en
P2093
Anne E Bygrave
H Terence Cook
Joanna Warren
Josefina Cortes-Hernandez
Kirsten L Rose
Marina Botto
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0020243
P407
P577
2004-08-01T00:00:00Z