Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease
about
The macrophages in rheumatic diseasesPivotal roles of GM-CSF in autoimmunity and inflammationIRF5 promotes inflammatory macrophage polarization and TH1-TH17 responsesColony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritisBatf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.A cytokine-cytokine interaction in the assembly of higher-order structure and activation of the interleukine-3:receptor complex.GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.Future therapeutic targets in rheumatoid arthritis?Molecular control of steady-state dendritic cell maturation and immune homeostasis.Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor-α, in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human studyThe GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.Mavrilimumab: an evidence based review of its potential in the treatment of rheumatoid arthritisNimesulide improves the symptomatic and disease modifying effects of leflunomide in collagen induced arthritis.Hematopoietic colony-stimulating factors: new players in tumor-nerve interactions.Extravascular coagulation and the plasminogen activator/plasmin system in rheumatoid arthritis.Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation.The interface between cholinergic pathways and the immune system and its relevance to arthritisEpigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes.MOR103, a human monoclonal antibody to granulocyte-macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial.Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis.Differing roles for urokinase and tissue-type plasminogen activator in collagen-induced arthritisRegulation of haematopoiesis by growth factors - emerging insights and therapies.Molecular targets in immune-mediated diseases: focus on rheumatoid arthritis.Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy.Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokinesPreclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis.Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders.An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope.Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritisGranulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development.GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency.Managing macrophages in rheumatoid arthritis by reform or removal.Characterization of pathogenic human monoclonal autoantibodies against GM-CSF.GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survivalRole of Th17 cells in the pathogenesis of CNS inflammatory demyelination.Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisitaLymphocyte-derived cytokines in inflammatory arthritis.Role of the Gut Microbiome in Modulating Arthritis Progression in Mice.The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.
P2860
Q26765275-DBAE79E5-0BAC-4CA1-A73C-B984F3FBACDCQ26830824-B073EB61-BE02-4DBB-8682-B8845DCE978CQ28303437-580AC64E-920C-45BF-95E0-946705CCB395Q28601432-CFE4B5B4-B9EA-4E67-9DC7-A97B133E35D9Q31040402-EB49AD8E-361B-44E5-B15E-A25A9E161FECQ33234976-4EDDAD32-A95F-4396-89D2-545F503B854AQ33427864-908B1CD6-75A6-4B62-B887-4376F6FE93B1Q33839932-9101E0B1-2930-4D46-AAD3-9DA16068C274Q33841419-66EFE4B0-BE2A-41BA-B405-AE4DBDFB76B8Q33882051-273D18C1-5BDC-4343-86A9-0159BFEF2E86Q34187345-42E56F12-9923-489D-94B4-2F08F4CEE66BQ34304678-CE41F774-E3B4-4E44-820D-C6639A763E62Q34411088-56D2F682-ABBC-4CAF-84D0-E6F29E0FC89EQ34465735-33D95400-EE4C-4B4A-A575-EFB07658628EQ34663630-BC1C6573-1C5C-4537-988D-752AFFC3689BQ34923078-4E9ADB4D-8B6B-41E7-B3B6-BDC8A0C052DBQ34967884-17879BA6-5D5B-4A35-9D17-EF1572C4B1DFQ35228289-0DA882FD-D5A7-4AA5-AB05-FE20E4E7AABAQ35557911-9CE4D684-C9C6-43D6-A465-658B4C429D5EQ35605418-CD40D5F6-B211-4AB8-BE97-ED76E146BD84Q35605572-2A174622-0FF3-45A9-9173-A2D072557466Q35788850-7A072ED9-075E-421F-A1D5-27FEBCE5BB0AQ35790849-C27A19B7-8149-43BF-8C77-5809660B187CQ35911103-6F614DA6-4D96-4FA5-ACC6-581524C01F04Q35928330-F82AD65D-68F2-49E9-9F59-8B5D6EE11AFCQ35953412-848A62A1-C89B-4F2A-AE09-B37A4E95DE9EQ36150157-2A3B5E1F-935D-4739-8E2C-E0F1C49DF3BEQ36400200-5395AE5C-7E36-433E-A508-265DF5A458CEQ36459657-287CDA3C-8884-45C2-A3E2-B95BFDADACF2Q36603223-8F5F047C-6110-43BF-90A2-58EAC2286F94Q36633120-14253AF1-1ED6-40A3-8F7D-349F2DFDF009Q36793496-4AD59FF5-0232-4FC5-B4EB-990A384F8752Q36802184-56947BF7-0751-44A7-92D4-B9C806BB3815Q36835759-BCC40D0E-E382-4809-86C6-39B590A3F00DQ36916371-2A87DFD6-A6D0-4399-AE57-2AFBEEC4B124Q37053851-3C4EF88F-A595-42CC-AC64-F1372ED8EAFFQ37055162-C4EC8C93-C0AD-441A-B638-CCA2DE58642FQ37118786-7C35B62B-E1D9-436B-B28D-5D74D8857B4EQ37145101-F06ECCE2-FA9C-4A47-8C07-91D1A32184CCQ37306641-5270CCF9-517A-4789-AAF3-26C9ECAD81B6
P2860
Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease
description
2001 nî lūn-bûn
@nan
2001 թուականին հրատարակուած գիտական յօդուած
@hyw
2001 թվականին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Blockade of collagen-induced a ...... the effector phase of disease
@ast
Blockade of collagen-induced a ...... the effector phase of disease
@en
Blockade of collagen-induced a ...... the effector phase of disease
@nl
type
label
Blockade of collagen-induced a ...... the effector phase of disease
@ast
Blockade of collagen-induced a ...... the effector phase of disease
@en
Blockade of collagen-induced a ...... the effector phase of disease
@nl
prefLabel
Blockade of collagen-induced a ...... the effector phase of disease
@ast
Blockade of collagen-induced a ...... the effector phase of disease
@en
Blockade of collagen-induced a ...... the effector phase of disease
@nl
P2093
P2860
P3181
P356
P1476
Blockade of collagen-induced a ...... the effector phase of disease
@en
P2093
E L Braine
I K Campbell
J A Hamilton
P2860
P2888
P3181
P356
10.1186/AR318
P407
P577
2001-01-01T00:00:00Z
P5875
P6179
1039642122