Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies - Wikidata - wikimedia - TriplyDB

Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies

Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies

http://www.wikidata.org/entity/Q24805056

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The Finnish lapphund retinal atrophy locus maps to the centromeric region of CFA9 Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertension.LRTae: improving statistical power for genetic association with case/control data when phenotype and/or genotype misclassification errors are present The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program.Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model.Using public control genotype data to increase power and decrease cost of case-control genetic association studies.Intermediate sized CGG repeats are not a common cause of idiopathic premature ovarian failure GWAPower: a statistical power calculation software for genome-wide association studies with quantitative traits.Genetic epidemiology of tuberculosis susceptibility: impact of study design Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.Tuberculosis as a complex trait: impact of genetic epidemiological study design Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study.The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases.Accuracy of phenotyping of autistic children based on Internet implemented parent report.Genome-wide association studies of antidepressant outcome: a brief review.Genome-wide association scan for variants associated with early-onset prostate cancer Genetic polymorphisms in transforming growth factor beta-1 (TGFB1) and childhood asthma and atopy.Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.ANLN truncation causes a familial fatal acute respiratory distress syndrome in Dalmatian dogs Association of markers at chromosome 15q14 in Chinese patients with moderate to high myopia.Power and sample size calculations for SNP association studies with censored time-to-event outcomes.Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs.Non-replication and inconsistency in the genome-wide association setting.Electronic medical records for genetic research: results of the eMERGE consortium Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane.Validation of electronic medical record-based phenotyping algorithms: results and lessons learned from the eMERGE network The complex genetics of multiple sclerosis: pitfalls and prospects "Noisy beets": impact of phenotyping errors on genomic predictions for binary traits in Beta vulgaris Single-variant and multi-variant trend tests for genetic association with next-generation sequencing that are robust to sequencing error.Impact of measurement error on testing genetic association with quantitative traits.The genetics of diabetic complications.Detecting genes in complex disease: does phenotype accuracy limit the horizon?Detecting new neurodegenerative disease genes: does phenotype accuracy limit the horizon?The association of the dopamine transporter gene and the dopamine receptor 2 gene with delirium, a meta-analysis.Genome-wide association study of insect bite hypersensitivity in Dutch Shetland pony mares.Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.The Impact of Diagnostic Code Misclassification on Optimizing the Experimental Design of Genetic Association Studies.Robust tests for single-marker analysis in case-control genetic association studies.

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Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies

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Power and sample size calculat ...... ol genetic association studies

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Chad Haynes

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Derek Gordon

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P2860

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

From genotypes to genes: doubling the sample size

"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits.

AN INVESTIGATION OF THE EFFECT OF MISCLASSIFICATION ON THE PROPERTIES OF CHI-2-TESTS IN THE ANALYSIS OF CATEGORICAL DATA.

Definition of the phenotype.

The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances.

Genetic associations in large versus small studies: an empirical assessment.

Genetic associations: false or true?

Back to the future: the 'old-fashioned' way to new medications for neurodegeneration.

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15819990

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