Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). - Wikidata - wikimedia - TriplyDB

Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).

Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).

http://www.wikidata.org/entity/Q24815571

about

Combination treatment with progesterone and vitamin D hormone may be more effective than monotherapy for nervous system injury and disease Bile salts of vertebrates: structural variation and possible evolutionary significance Structural considerations of vitamin D signaling Marine invertebrate xenobiotic-activated nuclear receptors: their application as sensor elements in high-throughput bioassays for marine bioactive compounds Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership COMPLEX EVOLUTION OF BILE SALTS IN BIRDS Diversity of bile salts in fish and amphibians: evolution of a complex biochemical pathway Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites Functional evolution of the vitamin D and pregnane X receptors.Evolution of pharmacologic specificity in the pregnane X receptor.The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Evaluation of computational docking to identify pregnane X receptor agonists in the ToxCast database.Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently Functional Divergence of the Nuclear Receptor NR2C1 as a Modulator of Pluripotentiality During Hominid Evolution.The environmental estrogen, nonylphenol, activates the constitutive androstane receptor.Functional evolution of the pregnane X receptor.Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds.Cross-species comparative toxicogenomics as an aid to safety assessment.Evolution of the bile salt nuclear receptor FXR in vertebrates Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer.Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species Ligand specificity and evolution of liver X receptors.Machine learning methods and docking for predicting human pregnane X receptor activation.Expression and regulation of the vitamin D receptor in the zebrafish, Danio rerio.PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics.The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation.Intrinsic disorder in nuclear hormone receptors.Identification and expression of multiple CYP1-like and CYP3-like genes in the bivalve mollusk Mytilus edulis.Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio)Vitamin D: calcium and bone homeostasis during evolution.Molecular adaptation and resilience of the insect's nuclear receptor USP Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus.Single-Nucleotide Variations of the Human Nuclear Hormone Receptor Genes in 60,000 Individuals.Drug Interactions with St. John's Wort In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets

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P2860

Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).

http://www.wikidata.org/entity/Q24815571

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Evolutionary selection across ...... titutive androstane receptors)

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Evolutionary selection across ...... itutive androstane receptors).

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Evolutionary selection across ...... itutive androstane receptors).

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Evolutionary selection across ...... titutive androstane receptors)

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Evolutionary selection across ...... itutive androstane receptors).

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Evolutionary selection across ...... titutive androstane receptors)

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Evolutionary selection across ...... itutive androstane receptors).

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Nuclear receptor

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Erin G Schuetz

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Kazuto Yasuda

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Lee R Hagey

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P2860

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

Noncalcemic Actions of Vitamin D Receptor Ligands

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin

Vitamin D receptor as an intestinal bile acid sensor

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution.

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10.1186/1478-1336-3-2

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Matthew D. Krasowski

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7566693

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16197547

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1262763

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