Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
about
Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvementEnzymatic capture of an extrahelical thymine in the search for uracil in DNAImpact of linker strain and flexibility in the design of a fragment-based inhibitorMcm2 phosphorylation and the response to replicative stressThe Chromone Alkaloid, Rohitukine, Affords Anti-Cancer Activity via Modulating Apoptosis Pathways in A549 Cell Line and Yeast Mitogen Activated Protein Kinase (MAPK) PathwayIdentification of novel microRNAs in Hevea brasiliensis and computational prediction of their targetsMimicking damaged DNA with a small molecule inhibitor of human UNG2.Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubationExpression profile of small RNAs in Acacia mangium secondary xylem tissue with contrasting lignin content - potential regulatory sequences in monolignol biosynthetic pathway.Saccharomyces cerevisiae as a model system to study the response to anticancer agents.Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.Dynamics of uracil and 5-fluorouracil in DNA.UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.Populations adapt to fluctuating selection using derived and ancestral allelic diversity.OCDB: a database collecting genes, miRNAs and drugs for obsessive-compulsive disorderUracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration.Participation of DNA repair in the response to 5-fluorouracil.Uracil in DNA: consequences for carcinogenesis and chemotherapyImpairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites.DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically.RNA-based 5-fluorouracil toxicity requires the pseudouridylation activity of Cbf5p.The applications of the novel polymeric fluoropyrimidine F10 in cancer treatment: current evidence.Targeting nuclear thymidylate biosynthesis.5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells.Anti-miR-155 oligonucleotide enhances chemosensitivity of U251 cell to taxol by inducing apoptosis.Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.Arabidopsis uracil DNA glycosylase (UNG) is required for base excision repair of uracil and increases plant sensitivity to 5-fluorouracil.Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase.Mechanisms of base selection by the Escherichia coli mispaired uracil glycosylase.High resolution mapping of modified DNA nucleobases using excision repair enzymes.MicroRNAome of splenic macrophages in hypersplenism due to portal hypertension in hepatitis B virus-related cirrhosis.Ung1p-mediated uracil-base excision repair in mitochondria is responsible for the petite formation in thymidylate deficient yeast.Probiotic therapy reduces inflammation and improves intestinal morphology in rats with induced oral mucositis.
P2860
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P2860
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
description
2006 nî lūn-bûn
@nan
2006 թուականին հրատարակուած գիտական յօդուած
@hyw
2006 թվականին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@ast
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@en
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@nl
type
label
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@ast
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@en
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@nl
prefLabel
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@ast
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@en
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@nl
P2093
P2860
P3181
P356
P1476
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast
@en
P2093
James T Stivers
Lauren Seiple
Miral Dizdaroglu
Pawel Jaruga
P2860
P304
P3181
P356
10.1093/NAR/GKJ430
P407
P577
2006-01-01T00:00:00Z