Lysosomal cathepsins and their regulation in aging and neurodegeneration
about
Using the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosisC9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling.Amino acid homeostasis and signalling in mammalian cells and organisms.Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress.Lysosomal processing of progranulinCysteine proteases in atherosclerosis.Serpin1 and WSCP differentially regulate the activity of the cysteine protease RD21 during plant development in Arabidopsis thalianaSkeletal Muscle Lysosomal Function via Cathepsin Activity Measurement.Lysosomes as Oxidative Targets for Cancer TherapyProteostasis, oxidative stress and aging.Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss.Cystatin C deficiency suppresses tumor growth in a breast cancer model through decreased proliferation of tumor cells.Taking out the garbage: cathepsin D and calcineurin in neurodegeneration.Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration.The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease.An Aspartyl Cathepsin Targeted PET Agent: Application in an Alzheimer's Disease Mouse Model.Dysfunction of Membrane Trafficking Leads to Ischemia-Reperfusion Injury After Transient Cerebral Ischemia.The protease inhibitor E64d improves ox-LDL-induced endothelial dysfunction in human aortic endothelial cells.Increased Levels of 27-Hydroxycholesterol Induced by Dietary Cholesterol in Brain Contribute to Learning and Memory Impairment in Rats.Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.Differential role of calpain-dependent protein cleavage in intermediate and long-term operant memory in Aplysia.Functional characterization of single-domain cystatin-like cysteine proteinase inhibitors expressed by the trematode Fasciola hepatica.Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers.Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases.Human brain gene expression profiles of the cathepsin V and cathepsin L cysteine proteases, with the PC1/3 and PC2 serine proteases, involved in neuropeptide production.Hypoxia-ischemia alters distribution of lysosomal proteins in rat cortex and hippocampusEarly lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice
P2860
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P2860
Lysosomal cathepsins and their regulation in aging and neurodegeneration
description
2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@ast
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@en
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@nl
type
label
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@ast
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@en
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@nl
prefLabel
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@ast
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@en
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@nl
P2093
P3181
P1476
Lysosomal cathepsins and their regulation in aging and neurodegeneration
@en
P2093
Boris Turk
Veronika Stoka
P3181
P356
10.1016/J.ARR.2016.04.010
P577
2016-04-26T00:00:00Z