Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins - Wikidata - wikimedia - TriplyDB

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

http://www.wikidata.org/entity/Q26766379

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eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts.Human AATF/Che-1 forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis.Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes.Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer.p53 is required for brain growth but is dispensable for resistance to nutrient restriction during Drosophila larval development.The PI3K/AKT axis modulates AATF activity in Wilms' tumor cells

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Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

http://www.wikidata.org/entity/Q26766379

description

2016 nî lūn-bûn

@nan

2016 թուականին հրատարակուած գիտական յօդուած

@hyw

2016 թվականին հրատարակված գիտական հոդված

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2016年の論文

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2016年学术文章

@wuu

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

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name

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@ast

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@en

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

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type

label

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@ast

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@en

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@nl

prefLabel

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@ast

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@en

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

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FONC.2016.00034

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Frontiers in Oncology

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Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

@en

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Maurizio Fanciulli

http://www.w3.org/2001/XMLSchema#string

Simona Iezzi

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A human RNA polymerase II subunit is encoded by a recently generated multigene family

AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis

Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

AATF protects neural cells against oxidative damage induced by amyloid beta-peptide

AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4

Che-1 activates XIAP expression in response to DNA damage

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II

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34

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scholarly article

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3480353

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10.3389/FONC.2016.00034

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6

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2016-01-01T00:00:00Z

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26913241

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4753824

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