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The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer

The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer

http://www.wikidata.org/entity/Q26774678

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A multifaceted approach targeting NK cells for better treatment of cancer: focus on hematological malignancies Immunological and Translational Aspects of NK Cell-Based Antitumor Immunotherapies Renal Toxicities of Novel Agents Used for Treatment of Multiple Myeloma.Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours.Gene-modified NK-92MI cells expressing a chimeric CD16-BB-ζ or CD64-BB-ζ receptor exhibit enhanced cancer-killing ability in combination with therapeutic antibody.Natural Killer Cell Diversity in Viral Infection: Why and How Much?Precision glycocalyx editing as a strategy for cancer immunotherapy.High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status Humanized Mouse Models of Clinical Disease.γδ T Cell-Mediated Immunity to Cytomegalovirus Infection.The anti-tumor role of NK cells in vivo pre-activated and re-stimulated by interleukins in acute lymphoblastic leukemia.Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma.Cellular immunity augmentation in mainstream oncologic therapy Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an "Off-the-Shelf Immunotherapy" for Improvement in Cancer Treatment.Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival.In vitro differentiated plasmacytoid dendritic cells as a tool to induce anti-leukemia activity of natural killer cells.Chimeric antigen receptor (CAR)-modified natural killer cell-based immunotherapy and immunological synapse formation in cancer and HIV.A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity.B7H6-derived peptides trigger TNF-α-dependent immunostimulatory activity of lymphocytic NK92-MI cells.Taming Tumor Glycolysis and Potential Implications for Immunotherapy.Cellular immunotherapy for malignant gliomas.Avelumab: combining immune checkpoint inhibition and antibody-dependent cytotoxicity.Reduction of Relapse after Unrelated Donor Stem Cell Transplantation by KIR-Based Graft Selection.Engineering Natural Killer Cells for Cancer Immunotherapy.Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells.CD56 in the Immune System: More Than a Marker for Cytotoxicity?Natural Killer Cell (NK-92MI)-Based Therapy for Pulmonary Metastasis of Anaplastic Thyroid Cancer in a Nude Mouse Model.In Vitro Culture with Interleukin-15 Leads to Expression of Activating Receptors and Recovery of Natural Killer Cell Function in Acute Myeloid Leukemia Patients.Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity.Potentiation of Natural Killer Cells for Cancer Immunotherapy: A Review of Literature Natural Killer Cell Memory: Progress and Implications The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development.Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway.Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers.Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells.Acquisition of cell migration defines NK cell differentiation from hematopoietic stem cell precursors.Natural killer cell: An immuno-oncology novel target for cancer therapy?A new therapeutic potential for cancers: One CAR with 2 different engines!Nano-Pulse Stimulation Ablates Orthotopic Rat Hepatocellular Carcinoma and Induces Innate and Adaptive Memory Immune Mechanisms that Prevent Recurrence.

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The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer

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Rayne H Rouce

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Natural killer cell mediated antibody-dependent cellular cytotoxicity in tumor immunotherapy with therapeutic antibodies

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells

Natural killer cell biology: an update and future directions

Improving the outcome of leukemia by natural killer cell-based immunotherapeutic strategies

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells

Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11

Advantages and applications of CAR-expressing natural killer cells

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire

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