Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors

Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors

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http://www.wikidata.org/entity/Q26783710
Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124.iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling.Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3.CDK1 interacts with iASPP to regulate colorectal cancer cell proliferation through p53 pathway.Wild-type and mutant p53 differentially modulate miR-124/iASPP feedback following pohotodynamic therapy in human colon cancer cell line.Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation.Sertad1 antagonizes iASPP function by hindering its entrance into nuclei to interact with P53 in leukemic cells.The 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction.P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint.Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma.Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP.Role of Kruppel-like factor 4 in regulating inhibitor of apoptosis-stimulating protein of p53 in the progression of gastric cancer.B7H3 As a Promoter of Metastasis and Promising Therapeutic Target
P2860

Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors

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http://www.wikidata.org/entity/Q26783710
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2015 nî lūn-bûn
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2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2015 թվականի օգոստոսին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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type
label
Reactivating p53 functions by ...... tunity in p53 wild-type tumors
@ast
Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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prefLabel
Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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Reactivating p53 functions by ...... tunity in p53 wild-type tumors
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P2093
P275
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P5008
P577
P5875
P698
P921
P932