Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors

Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors

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http://www.wikidata.org/entity/Q26824325
High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors.A membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the Gloeobacter violaceus ion channel.Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator.Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.The development of novel polypharmacological agents targeting the multiple binding sites of nicotinic acetylcholine receptors.Nicotinic acetylcholine receptors at the single-channel level.The M4 Transmembrane α-Helix Contributes Differently to Both the Maturation and Function of Two Prokaryotic Pentameric Ligand-gated Ion Channels.Pentameric ligand-gated ion channels exhibit distinct transmembrane domain archetypes for folding/expression and function.Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics.Enantiomeric barbiturates bind distinct inter- and intrasubunit binding sites in a nicotinic acetylcholine receptor (nAChR).General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type A Receptors (GABAARs).Recent progress on the molecular pharmacology of propofol.An allosteric link connecting the lipid-protein interface to the gating of the nicotinic acetylcholine receptor.Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity
P2860

Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors

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http://www.wikidata.org/entity/Q26824325
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2015 nî lūn-bûn
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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@ast
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@en
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
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label
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@ast
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@en
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@nl
prefLabel
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@ast
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@en
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@nl
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P356
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Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
@en
P2093
P2860
P304
P31
P356
10.1016/J.NEUROPHARM.2014.10.002
P407
P433
P478
P577
P698
P921
P932