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Renal transport of uric acid: evolving concepts and uncertainties

Renal transport of uric acid: evolving concepts and uncertainties

http://www.wikidata.org/entity/Q26829446

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Linking uric acid metabolism to diabetic complications Natural Products Improving Hyperuricemia with Hepatorenal Dual Effects Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids Pathophysiological and physicochemical basis of ammonium urate stone formation in dolphins.Hyperuricemia and deterioration of renal function in autosomal dominant polycystic kidney disease.Association of a polymorphism in a gene encoding a urate transporter with CKD progression.Paracellular route is the major urate transport pathway across the blood-placental barrier Uric acid in the pathogenesis of metabolic, renal, and cardiovascular diseases: A review.The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease, morbidity and mortality Association between Dietary Magnesium Intake and Hyperuricemia Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy.Is Uric Acid a Missing Link between Previous Gestational Diabetes Mellitus and the Development of Type 2 Diabetes at a Later Time of Life?Potential causal associations between vitamin D and uric acid: Bidirectional mediation analysis.A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties Hyperuricemia after orthotopic liver transplantation: divergent associations with progression of renal disease, incident end-stage renal disease, and mortality Discovery of URAT1 SNPs and association between serum uric acid levels and URAT1.Management of Chronic Kidney Disease: The Relationship Between Serum Uric Acid and Development of Nephropathy Predicting allopurinol response in patients with gout Supratherapeutic dose evaluation and effect of lesinurad on cardiac repolarization: a thorough QT/QTc study Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations.The Role of Uric Acid and Methyl Derivatives in the Prevention of Age-Related Neurodegenerative Disorders.Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.Evaluation and Quantitative Prediction of Renal Transporter-Mediated Drug-Drug Interactions.Time to target uric acid to retard CKD progression.Hyperuricemia, Hypertension, and Chronic Kidney Disease: an Emerging Association.Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study).Recent advances in understanding and managing gout Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study).Prenatal Earthquake Exposure and Midlife Uric Acid Levels Among Chinese Adults.Gout: An old disease in new perspective - A review.Physiological functions and pathogenic potential of uric acid: A review.Association between serum uric acid and metabolic syndrome components in prepubertal obese children (Tanner Stage I) from Nuevo León, Mexico - a preliminary study.Asymptomatic hyperuricemia and chronic kidney disease: Narrative review of a treatment controversial.[Hyperuricemia - more than gout : Impact on cardiovascular risk and renal insufficiency].Efficacy of Fenugreek-based bionanocomposite on renal dysfunction and endogenous intoxication in high-calorie diet-induced obesity rat model-comparative study.Determination of lesinurad in rat plasma by a UHPLC-MS/MS assay.Dietary Sodium Modifies Serum Uric Acid Concentrations in Humans.Fructus Gardenia Extract ameliorates oxonate-induced hyperuricemia with renal dysfunction in mice by regulating organic ion transporters and mOIT3.

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Renal transport of uric acid: evolving concepts and uncertainties

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2012 nî lūn-bûn

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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Renal transport of uric acid: evolving concepts and uncertainties

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Renal transport of uric acid: evolving concepts and uncertainties

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Renal transport of uric acid: evolving concepts and uncertainties

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Renal transport of uric acid: evolving concepts and uncertainties

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Renal transport of uric acid: evolving concepts and uncertainties

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Advances in Chronic Kidney Disease

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Renal transport of uric acid: evolving concepts and uncertainties

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Ion Alexandru Bobulescu

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Orson W. Moe

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P2860

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

A multidrug resistance transporter from human MCF-7 breast cancer cells

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9)

Molecular identification of a renal urate anion exchanger that regulates blood urate levels

Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules

A 1.1-Mb transcript map of the hereditary hemochromatosis locus

Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)

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