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Comparative genomics of defense systems in archaea and bacteria

Comparative genomics of defense systems in archaea and bacteria

http://www.wikidata.org/entity/Q26829917

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High-resolution transcriptome maps reveal strain-specific regulatory features of multiple Campylobacter jejuni isolates Viruses and mobile elements as drivers of evolutionary transitions Evolutionary Ecology of Prokaryotic Immune Mechanisms Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways Classification and evolution of type II CRISPR-Cas systems A virocentric perspective on the evolution of life To be or not to be: regulation of restriction-modification systems and other toxin-antitoxin systems Molecular mechanisms of CRISPR-mediated microbial immunity The common ancestor of archaea and eukarya was not an archaeon Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3 Resistance and tolerance to foreign elements by prokaryotic immune systems - curating the genome Population cycles and species diversity in dynamic Kill-the-Winner model of microbial ecosystems An Enrichment of CRISPR and Other Defense-Related Features in Marine Sponge-Associated Microbial Metagenomes A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism.CARF and WYL domains: ligand-binding regulators of prokaryotic defense systems Dark matter in archaeal genomes: a rich source of novel mobile elements, defense systems and secretory complexes.Annotation and Classification of CRISPR-Cas Systems.Virus-host interplay in high salt environments.A locus encoding variable defence systems against invading DNA identified in Streptococcus suis.An updated evolutionary classification of CRISPR-Cas systems.Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.Comprehensive classification of the PIN domain-like superfamily Pseudo-chaotic oscillations in CRISPR-virus coevolution predicted by bifurcation analysis.Unravelling the structural and mechanistic basis of CRISPR-Cas systems.MIMIVIRE is a defence system in mimivirus that confers resistance to virophage.Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes.The interplay of restriction-modification systems with mobile genetic elements and their prokaryotic hosts.Comparative genomic analysis of Mycobacterium iranicum UM_TJL against representative mycobacterial species suggests its environmental origin.Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question.Genomics-Based Exploration of Virulence Determinants and Host-Specific Adaptations of Pseudomonas syringae Strains Isolated from Grasses Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergence Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles.The double-edged sword of Lamarck: comment on "Diversity, evolution, and therapeutic applications of small RNAs in prokaryotic and eukaryotic immune systems" by Edwin L. Cooper and Nicola Overstreet.Comparative analysis of CRISPR cassettes from the human gut metagenomic contigs Phage and bacteria support mutual diversity in a narrowing staircase of coexistence.Insights from 20 years of bacterial genome sequencing.Improving the efficiency of transposon mutagenesis in Salmonella enteritidis by overcoming host-restriction barriers.Immunity, suicide or both? Ecological determinants for the combined evolution of anti-pathogen defense systems.

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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Comparative genomics of defense systems in archaea and bacteria

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K. S. Makarova

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Y. I. Wolf

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Creative Commons Attribution-NonCommercial 3.0 Unported

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A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes.

Bacterial toxin-antitoxin systems: more than selfish entities?

RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Nucleoside triphosphate-dependent restriction enzymes

Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes

Mini-F plasmid genes that couple host cell division to plasmid proliferation

A vast collection of microbial genes that are toxic to bacteria

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

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10.1093/NAR/GKT157

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