Proteostasis and longevity: when does aging really begin?
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J protein mutations and resulting proteostasis collapseEngineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced ActivityHeat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseasesGraded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome PathwayModulation of the maladaptive stress response to manage diseases of protein foldingRole of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative DiseasesHeat shock proteins in neurodegenerative disorders and agingMechanisms of protein balance in skeletal muscle.Using pharmacological chaperones to restore proteostasisMetabolome and proteome changes with aging in Caenorhabditis elegans.Fibrosis: ultimate and proximate causesBlue journal conference. Aging and susceptibility to lung disease.Alpha-synuclein levels in blood plasma decline with healthy aging.Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively.Tissue-specific autophagy responses to aging and stress in C. elegansAbnormal Osmotic Avoidance Behavior in C. elegans Is Associated with Increased Hypertonic Stress Resistance and Improved ProteostasisAneuploidy shortens replicative lifespan in Saccharomyces cerevisiaeThe Aging EpigenomeIncreased levels of hyper-stable protein aggregates in plasma of older adults.Alzheimer-related protein APL-1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans.Royal jelly promotes DAF-16-mediated proteostasis to tolerate β-amyloid toxicity in C. elegans model of Alzheimer's disease.Lifespan-regulating genes in C. elegans.Mechanisms of neuronal homeostasis: Autophagy in the axon.Drug Discovery in Fish, Flies, and Worms.Small heat shock proteins in ageing and age-related diseases.Endoplasmic reticulum proteostasis impairment in agingCell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span.Searching for the elusive mitochondrial longevity signal in C. elegans.C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stressIron promotes protein insolubility and aging in C. elegans.Proteostasis collapse, inter-tissue communication, and the regulation of aging at the organismal level.Heat shock in the springtime.Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans.Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging.Mitochondrial proteostasis as a shared characteristic of slowed aging: the importance of considering cell proliferation.Q&A: Trash talk: disposal and remote degradation of neuronal garbage.The Systems Biology of Single-Cell Aging
P2860
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P2860
Proteostasis and longevity: when does aging really begin?
description
2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
@yue
2014年論文
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2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Proteostasis and longevity: when does aging really begin?
@ast
Proteostasis and longevity: when does aging really begin?
@en
Proteostasis and longevity: when does aging really begin?
@nl
type
label
Proteostasis and longevity: when does aging really begin?
@ast
Proteostasis and longevity: when does aging really begin?
@en
Proteostasis and longevity: when does aging really begin?
@nl
prefLabel
Proteostasis and longevity: when does aging really begin?
@ast
Proteostasis and longevity: when does aging really begin?
@en
Proteostasis and longevity: when does aging really begin?
@nl
P2860
P3181
P356
P1433
P1476
Proteostasis and longevity: when does aging really begin?
@en
P2093
John Labbadia
Richard I. Morimoto
P2860
P3181
P356
10.12703/P6-7
P407
P577
2014-01-01T00:00:00Z