Molecular pathways: protein methyltransferases in cancer
about
Intrinsic protein disorder in histone lysine methylation.Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic MutationsA High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase ScreeningDiscovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation ApproachStructural diversity of the epigenetics pocketome.Emerging therapeutic targets for synovial sarcoma.Structural insights into binding of small molecule inhibitors to Enhancer of Zeste Homolog 2.Genetic alterations of histone lysine methyltransferases and their significance in breast cancerEPMA position paper in cancer: current overview and future perspectives.Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial SarcomaEpigenetic Modulation of Human Podocyte Vitamin D Receptor in HIV MilieuCharacterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma.Bromodomains and their pharmacological inhibitors.Chromatin modifications remodel cardiac gene expression.Epigenetic pathway targets for the treatment of disease: accelerating progress in the development of pharmacological tools: IUPHAR Review 11.Epigenetics of the failing heart.A global assessment of cancer genomic alterations in epigenetic mechanisms.Prediction of mycoplasma hominis proteins targeting in mitochondria and cytoplasm of host cells and their implication in prostate cancer etiology.Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques.Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer.Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma.Probing the epigenomeProtein methyltransferase inhibitors as precision cancer therapeutics: a decade of discovery.
P2860
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P2860
Molecular pathways: protein methyltransferases in cancer
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Molecular pathways: protein methyltransferases in cancer
@ast
Molecular pathways: protein methyltransferases in cancer
@en
Molecular pathways: protein methyltransferases in cancer
@nl
type
label
Molecular pathways: protein methyltransferases in cancer
@ast
Molecular pathways: protein methyltransferases in cancer
@en
Molecular pathways: protein methyltransferases in cancer
@nl
prefLabel
Molecular pathways: protein methyltransferases in cancer
@ast
Molecular pathways: protein methyltransferases in cancer
@en
Molecular pathways: protein methyltransferases in cancer
@nl
P3181
P1476
Molecular pathways: protein methyltransferases in cancer
@en
P2093
R. A. Copeland
P304
P3181
P356
10.1158/1078-0432.CCR-13-0223
P407
P577
2013-12-01T00:00:00Z