Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling - Wikidata - wikimedia - TriplyDB

Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling

Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling

http://www.wikidata.org/entity/Q26864995

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Monosodium glutamate-induced oxidative kidney damage and possible mechanisms: a mini-review Glutamate and tumor-associated epilepsy: glial cell dysfunction in the peritumoral environment MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development Altered serine/threonine kinase activity in schizophrenia Reduction in phencyclidine induced sensorimotor gating deficits in the rat following increased system xc⁻ activity in the medial prefrontal cortex.Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture.Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.Glutamate as a neurotransmitter in the healthy brain Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: a light and electron microscopic study Change of cystine/glutamate antiporter expression in ethanol-dependent rats.Behavioral assessment of acute inhibition of system xc (-) in rats Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A "central hub" in schizophrenia pathophysiology?Redox-based therapeutics in neurodegenerative disease.Aggrecan and chondroitin-6-sulfate abnormalities in schizophrenia and bipolar disorder: a postmortem study on the amygdala N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans.Thiol redox homeostasis in neurodegenerative disease Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement.Effects of ceftriaxone on GLT1 isoforms, xCT and associated signaling pathways in P rats exposed to ethanol.Ceftriaxone attenuates acquisition and facilitates extinction of cocaine-induced suppression of saccharin intake in C57BL/6J mice A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc- Mediates Aglycemic Neuronal Cell Death Interleukin 1β Regulation of the System xc- Substrate-specific Subunit, xCT, in Primary Mouse Astrocytes Involves the RNA-binding Protein HuR Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia Pituitary Adenylate cyclase-activating polypeptide orchestrates neuronal regulation of the astrocytic glutamate-releasing mechanism system xc (.).N-acetylcysteine decreases binge eating in a rodent model Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.Synaptic glutamate spillover due to impaired glutamate uptake mediates heroin relapse Neurotransmitter signaling in the pathophysiology of microglia.Glutamate drugs and pharmacogenetics of OCD: a pathway-based exploratory approach.N-Acetylcysteine and metabotropic glutamate receptors: implications for the treatment of schizophrenia: a literature review.Glutamate receptors in the kidney.Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology model Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.Permanent dynamic transporter-mediated turnover of glutamate across the plasma membrane of presynaptic nerve terminals: arguments in favor and against.Emerging roles of system [Formula: see text] antiporter and its inhibition in CNS disorders.Metabolomics reveals distinct neurochemical profiles associated with stress resilience.Accumbens Mechanisms for Cued Sucrose Seeking.The good and bad news about glutamate in drug addiction.l-DOPA-induced dyskinesia and neuroinflammation: do microglia and astrocytes play a role?Parkinson's disease: Microglial/macrophage-induced immunoexcitotoxicity as a central mechanism of neurodegeneration Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed.

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Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling

http://www.wikidata.org/entity/Q26864995

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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name

Thinking outside the cleft to ...... ogical glutamatergic signaling

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Thinking outside the cleft to ...... ogical glutamatergic signaling

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Thinking outside the cleft to ...... ogical glutamatergic signaling

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Thinking outside the cleft to ...... ogical glutamatergic signaling

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Thinking outside the cleft to ...... ogical glutamatergic signaling

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Thinking outside the cleft to ...... ogical glutamatergic signaling

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Pharmacological Reviews

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Thinking outside the cleft to ...... ogical glutamatergic signaling

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Doug Lobner

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Richard Bridges

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Victoria Lutgen

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P2860

Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria

ASCT-1 is a neutral amino acid exchanger with chloride channel activity

Interaction of L-cysteine with a human excitatory amino acid transporter

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain

The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine

Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons

Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking

The glutamate story

Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo

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780-802

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10.1124/PR.110.003889

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