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Factor XI as a target for antithrombotic therapy

Factor XI as a target for antithrombotic therapy

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Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.Factor XIa inhibitors: A review of the patent literature.Medical device-induced thrombosis: what causes it and how can we prevent it?Heparan sulfate/heparin glycosaminoglycan binding alters inhibitory profile and enhances anticoagulant function of conserved Amblyomma americanum tick saliva serpin 19.Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis.Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.Fragment-Based Lead Generation of 5-Phenyl-1-pyrazole-3-carboxamide Derivatives as Leads for Potent Factor Xia Inhibitors

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Factor XI as a target for antithrombotic therapy

http://www.wikidata.org/entity/Q26865486

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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Factor XI as a target for antithrombotic therapy

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J.DRUDIS.2014.05.018

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Drug Discovery Today

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Factor XI as a target for antithrombotic therapy

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Charles E. Bane

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David Gailani

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P2860

Defective thrombus formation in mice lacking coagulation factor XII

Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa

Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors

Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice

Location of the disulfide bonds in human coagulation factor XI: the presence of tandem apple domains

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

Structure and function of factor XI

Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa

Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa

Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.

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1454-8

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scholarly article

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10.1016/J.DRUDIS.2014.05.018

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9

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19

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2014-09-01T00:00:00Z

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4167190

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