about
The PI3K/Akt Pathway in Tumors of Endocrine TissuesNuclear PI3K signaling in cell growth and tumorigenesisTurning off AKT: PHLPP as a drug targetMicroRNA and signal transduction pathways in tumor radiation responseAkt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotencyEx vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.Cowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells.Signaling specificity in the Akt pathway in biology and disease.Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy.Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy.A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cellsPlant proteolytic enzyme papain abrogates angiogenic activation of human umbilical vein endothelial cells (HUVEC) in vitro.Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway.Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling.Diverse involvement of isoforms and gene aberrations of Akt in human lung carcinomas.Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1).Mitochondria Related Pathway Is Essential for Polysaccharides Purified from Sparassis crispa Mediated Neuro-Protection against Glutamate-Induced Toxicity in Differentiated PC12 Cells.NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies.Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes.Activated Acinus boosts basal autophagyThe PI3K/Akt1 pathway enhances steady-state levels of FANCL.Trastuzumab as a preoperative monotherapy does not inhibit HER2 downstream signaling in HER2-positive breast cancer.Aloe-emodin suppresses esophageal cancer cell TE1 proliferation by inhibiting AKT and ERK phosphorylation.Phytochemicals from cruciferous vegetables, epigenetics, and prostate cancer prevention.Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation.Sirt2 deacetylase is a novel AKT binding partner critical for AKT activation by insulinRole of regulatory T cells in pathogenesis and biological therapy of multiple sclerosis.The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development.Mitochondrial-epigenetic crosstalk in environmental toxicology.Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer.Association between high expression of phosphorylated Akt and mammalian target of rapamycin and improved survival in salivary gland adenoid cystic carcinoma.Nuclear Lipids in the Nervous System: What they do in Health and Disease.Targeting protein kinase-b3 (akt3) signaling in melanoma.Signaling coupled epigenomic regulation of gene expression.AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma.PD-L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation.Abnormal Akt signalling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells.Gad8 Protein Is Found in the Nucleus Where It Interacts with the MluI Cell Cycle Box-binding Factor (MBF) Transcriptional Complex to Regulate the Response to DNA Replication Stress.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
The emerging multiple roles of nuclear Akt
@ast
The emerging multiple roles of nuclear Akt
@en
The emerging multiple roles of nuclear Akt
@nl
type
label
The emerging multiple roles of nuclear Akt
@ast
The emerging multiple roles of nuclear Akt
@en
The emerging multiple roles of nuclear Akt
@nl
prefLabel
The emerging multiple roles of nuclear Akt
@ast
The emerging multiple roles of nuclear Akt
@en
The emerging multiple roles of nuclear Akt
@nl
P2093
P3181
P1476
The emerging multiple roles of nuclear Akt
@en
P2093
Alberto M. Martelli
Andrea Ognibene
Daniela Bressanin
Giovanna Tabellini
Kaoru Goto
Lucio Cocco
P304
P3181
P356
10.1016/J.BBAMCR.2012.08.017
P407
P577
2012-12-01T00:00:00Z