Monoacylglycerol lipase - a target for drug development?

Monoacylglycerol lipase - a target for drug development?

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http://www.wikidata.org/entity/Q26998964
Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applicationsThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.Metabolism of endocannabinoids and related N-acylethanolamines: canonical and alternative pathways.Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerolPostnatal ethanol exposure alters levels of 2-arachidonylglycerol-metabolizing enzymes and pharmacological inhibition of monoacylglycerol lipase does not cause neurodegeneration in neonatal mice.Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain.Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.Modulating the endocannabinoid system in human health and disease--successes and failuresMembrane phospholipid bilayer as a determinant of monoacylglycerol lipase kinetic profile and conformational repertoire.Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase.Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitorsProteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition.The evolving role of the endocannabinoid system in gynaecological cancer.Recent discoveries on absorption of dietary fat: Presence, synthesis, and metabolism of cytoplasmic lipid droplets within enterocytes.Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile.
P2860

Monoacylglycerol lipase - a target for drug development?

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http://www.wikidata.org/entity/Q26998964
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Monoacylglycerol lipase - a target for drug development?
@ast
Monoacylglycerol lipase - a target for drug development?
@en
Monoacylglycerol lipase - a target for drug development?
@nl
type
label
Monoacylglycerol lipase - a target for drug development?
@ast
Monoacylglycerol lipase - a target for drug development?
@en
Monoacylglycerol lipase - a target for drug development?
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prefLabel
Monoacylglycerol lipase - a target for drug development?
@ast
Monoacylglycerol lipase - a target for drug development?
@en
Monoacylglycerol lipase - a target for drug development?
@nl
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P2860
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Monoacylglycerol lipase - a target for drug development?
@en
P2093
P2860
P304
P31
P3181
P356
10.1111/J.1476-5381.2012.01950.X
P407
P433
P478
P577
P5875
P698
P932