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Inflammasomes: mechanism of action, role in disease, and therapeutics

Inflammasomes: mechanism of action, role in disease, and therapeutics

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Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escape Questions and controversies in innate immune research: what is the physiological role of NLRP3?From Inflammation to Prostate Cancer: The Role of Inflammasomes The Nucleotide Oligomerization Domain-Like Receptors in Kidney Injury How Mouse Macrophages Sense What Is Going On.Nanoparticle-Based and Bioengineered Probes and Sensors to Detect Physiological and Pathological Biomarkers in Neural Cells Innate Immune Response in Brain, NF-Kappa B Signaling and Cystatins IL-18 and Cutaneous Inflammatory Diseases Myofibroblasts and lung fibrosis induced by carbon nanotube exposure Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways Cellular Stress Response and Immune Signaling in Retinal Ischemia-Reperfusion Injury The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation Inflammasomes and Natural Ingredients towards New Anti-Inflammatory Agents Carbon monoxide in the treatment of sepsis Immune Surveillance of the CNS following Infection and Injury Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation Inflammation-a Critical Appreciation of the Role of Myeloid Cells Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis Metabolic Disorder in Chronic Obstructive Pulmonary Disease (COPD) Patients: Towards a Personalized Approach Using Marine Drug Derivatives.Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.Inflammasome Activation Underlying Central Nervous System Deterioration in HIV-Associated Tuberculosis.Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Signaling Mediated by Toll-Like Receptor 5 Sensing of Pseudomonas aeruginosa Flagellin Influences IL-1β and IL-18 Production by Primary Fibroblasts Derived from the Human Cornea Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology?A high-fat diet impairs reproduction by decreasing the IL1β level in mice treated at immature stage.Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production.Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue.Huaier aqueous extract protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NLRP3 inflammasome activation.Globular Adiponectin Inhibits Lipopolysaccharide-Primed Inflammasomes Activation in Macrophages via Autophagy Induction: The Critical Role of AMPK Signaling.A genetic risk score is differentially associated with migraine with and without aura.AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation by 17β-Estradiol.Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model Anti-inflammatory effects of isoketocharbroic acid from brown alga, Sargassum micracanthum.The Neuroprotective Effect of Rapamycin as a Modulator of the mTOR-NF-κB Axis during Retinal Inflammation

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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2015 nî lūn-bûn

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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2015 թվականի հուլիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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Nature Medicine

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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Haitao Guo

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Jenny P-Y Ting

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Justin B Callaway

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Parkinson's Disease: Genetics and Pathogenesis

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

The NAIP/NLRC4 inflammasomes

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10.1038/NM.3893

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7

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21

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1048838933

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4519035

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