Role of cytokines in intervertebral disc degeneration: pain and disc content - Wikidata - wikimedia - TriplyDB

Role of cytokines in intervertebral disc degeneration: pain and disc content

Role of cytokines in intervertebral disc degeneration: pain and disc content

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Novel Insights into Acid-Sensing Ion Channels: Implications for Degenerative Diseases Molecular mechanisms of biological aging in intervertebral discs Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration Sex hormones and immune dimorphism Whole-body Vibration at Thoracic Resonance Induces Sustained Pain and Widespread Cervical Neuroinflammation in the Rat.Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics Nanoparticle fullerol alleviates radiculopathy via NLRP3 inflammasome and neuropeptides.A Novel Modality for Functional Imaging in Acute Intervertebral Disk Herniation via Tracking Leukocyte Infiltration.Plasmacytoid dendritic cells and memory T cells infiltrate true sequestrations stronger than subligamentous sequestrations: evidence from flow cytometric analysis of disc infiltrates.Elevated Production of Nociceptive CC-chemokines and sE-selectin in Patients with Low Back Pain and the Effects of Spinal Manipulation: A Non-randomized Clinical Trial.In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α.Collagen-derived N-acetylated proline-glycine-proline upregulates the expression of pro-inflammatory cytokines and extracellular matrix proteases in nucleus pulposus cells via the NF-κB and MAPK signaling pathways.IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration.Advanced glycation end products regulate anabolic and catabolic activities via NLRP3-inflammasome activation in human nucleus pulposus cells.Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs.Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc di Blocking the function of inflammatory cytokines and mediators by using IL-10 and TGF-β: a potential biological immunotherapy for intervertebral disc degeneration in a beagle model.Inflammation in intervertebral disc degeneration and regeneration Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBP Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting Genetic and functional studies of the intervertebral disc: a novel murine intervertebral disc model TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs Back pain was less explained than leg pain: a cross-sectional study using magnetic resonance imaging in low back pain patients with and without radiculopathy.Inflammatory profiles in canine intervertebral disc degeneration Photobiomodulation on human annulus fibrosus cells during the intervertebral disk degeneration: extracellular matrix-modifying enzymes.Biocompatibility and intradiscal application of a thermoreversible celecoxib-loaded poly-N-isopropylacrylamide MgFe-layered double hydroxide hydrogel in a canine model.Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells.Microarray based analysis of gene regulation by microRNA in intervertebral disc degeneration Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders.Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases.Mesenchymal stem cells: potential application in intervertebral disc regeneration.Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.NF-κB Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors Syndecan-4 in intervertebral disc and cartilage: Saint or synner?Expression levels of IL-17 and TNF-α in degenerated lumbar intervertebral discs and their correlation.Do mechanical strain and TNF-α interact to amplify pro-inflammatory cytokine production in human annulus fibrosus cells?SDF‑1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF‑κB pathway.OPG rs2073617 polymorphism is associated with upregulated OPG protein expression and an increased risk of intervertebral disc degeneration

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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Irving M. Shapiro

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Makarand V. Risbud

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Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism

Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons

Interferon-gamma: an overview of signals, mechanisms and functions

The heparan sulfate binding sequence of interferon-gamma increased the on rate of the interferon-gamma-interferon-gamma receptor complex formation

Tumor necrosis factor-alpha modulates matrix production and catabolism in nucleus pulposus tissue

Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration

TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc

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