Molecular insights on context-specific role of profilin-1 in cell migration - Wikidata - wikimedia - TriplyDB

Molecular insights on context-specific role of profilin-1 in cell migration

Molecular insights on context-specific role of profilin-1 in cell migration

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Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways.Threonine 89 Is an Important Residue of Profilin-1 That Is Phosphorylatable by Protein Kinase A A four actin-binding protein signature model for poor prognosis of patients with esophageal squamous cell carcinoma Profilin isoforms modulate astrocytic morphology and the motility of astrocytic processes Profilin1 regulates invadopodium maturation in human breast cancer cells Silencing profilin-1 inhibits gastric cancer progression via integrin β1/focal adhesion kinase pathway modulation Two functionally distinct sources of actin monomers supply the leading edge of lamellipodia BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study.In vivo MR and Fluorescence Dual-modality Imaging of Atherosclerosis Characteristics in Mice Using Profilin-1 Targeted Magnetic Nanoparticles.PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma.Profilin-1 versus profilin-2: two faces of the same coin?Dynamic localization of G-actin during membrane protrusion in neuronal motility.Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy.The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms.Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis.Profilin1 biology and its mutation, actin(g) in disease.Profilin Expression Is Regulated by Bone Morphogenetic Protein (BMP) in Osteoblastic Cells.Human profilin 1 is a negative regulator of CTL mediated cell-killing and migration.Structure-based virtual screening identifies small molecule inhibitor of the profilin1-actin interaction.A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells.

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Molecular insights on context-specific role of profilin-1 in cell migration

http://www.wikidata.org/entity/Q27008398

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2012 nî lūn-bûn

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2012 թուականին հրատարակուած գիտական յօդուած

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2012 թվականին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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name

Molecular insights on context-specific role of profilin-1 in cell migration

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Molecular insights on context-specific role of profilin-1 in cell migration

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Molecular insights on context-specific role of profilin-1 in cell migration

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Molecular insights on context-specific role of profilin-1 in cell migration

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Molecular insights on context-specific role of profilin-1 in cell migration

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Molecular insights on context-specific role of profilin-1 in cell migration

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prefLabel

Molecular insights on context-specific role of profilin-1 in cell migration

@ast

Molecular insights on context-specific role of profilin-1 in cell migration

@en

Molecular insights on context-specific role of profilin-1 in cell migration

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Cell Adhesion and Migration

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Molecular insights on context-specific role of profilin-1 in cell migration

@en

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Partha Roy

http://www.w3.org/2001/XMLSchema#string

Zhijie Ding

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Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors

The essential role of profilin in the assembly of actin for microspike formation.

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis

Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation

In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly

Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties

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442-449

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scholarly article

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1245937

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10.4161/CAM.21832

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5

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23076048

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3496682

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