Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention
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X region mutations of hepatitis B virus related to clinical severityViruses and cells intertwined since the dawn of evolutionHepatitis B virus molecular biology and pathogenesisDifferent Variants in Reverse Transcriptase Domain Determined by Ultra-deep Sequencing in Treatment-naïve and Treated Indonesian Patients Infected with Hepatitis B VirusHepatitis B virus infection in patients with blood disorders: a concise review in pediatric study.Regulation of multiple stages of hepadnavirus replication by the carboxyl-terminal domain of viral core protein in trans.Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathwaysUnveiling the roles of HBV polymerase for new antiviral strategiesAlteration of Mature Nucleocapsid and Enhancement of Covalently Closed Circular DNA Formation by Hepatitis B Virus Core Mutants Defective in Complete-Virion Formation.Modeling the functional state of the reverse transcriptase of hepatitis B virus and its application to probing drug-protein interaction.Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation.Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development.Hepatitis B virus spliced variants are associated with an impaired response to interferon therapy.Overview of hepatitis B viral replication and genetic variabilityComparative analysis of hepatitis B virus polymerase sequences required for viral RNA binding, RNA packaging, and protein priming.Recent advance of the hepatitis B virus inhibitors: a medicinal chemistry overview.Wild type HBx and truncated HBx: Pleiotropic regulators driving sequential genetic and epigenetic steps of hepatocarcinogenesis and progression of HBV-associated neoplasms.Synergistic Interactions between Hepatitis B Virus RNase H Antagonists and Other Inhibitors.Study on 2-arylthio-5-iodo pyrimidine derivatives as novel nonnucleoside inhibitors against hepatitis B virus DNA replication.Progressive accumulation of mutations in the hepatitis B virus genome and its impact on time to diagnosis of hepatocellular carcinoma.Mechanisms of Hepatitis B Virus Persistence.Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance.PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation.Mapping of Functional Subdomains in the Terminal Protein Domain of Hepatitis B Virus Polymerase.Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice.Common and Distinct Capsid and Surface Protein Requirements for Secretion of Complete and Genome-free Hepatitis B Virions.
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P2860
Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@ast
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@en
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@nl
type
label
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@ast
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@en
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@nl
prefLabel
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@ast
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@en
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@nl
P2860
P3181
P356
P1476
Hepatitis B virus reverse tran ...... ets for antiviral intervention
@en
P2093
Jianming Hu
Scott A Jones
P2860
P3181
P356
10.1038/EMI.2013.56
P407
P577
2013-09-01T00:00:00Z