FAK in cancer: mechanistic findings and clinical applications
about
Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapyFAK and paxillin, two potential targets in pancreatic cancerThe dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker valueRUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progressionTrial Watch: Immunogenic cell death inducers for anticancer chemotherapyMesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-βα-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturationFibronectin Modulates Cell Adhesion and Signaling to Promote Single Cell Migration of Highly Invasive Oral Squamous Cell CarcinomaPI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasionMicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1Activation of focal adhesion kinase through an interaction with β4 integrin contributes to tumorigenicity of colon cancerStructural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death.The Genome Conformation As an Integrator of Multi-Omic Data: The Example of Damage Spreading in CancerParis polyphylla Suppresses Proliferation and Vasculogenic Mimicry of Human Osteosarcoma Cells and Inhibits Tumor Growth In Vivo.Regulation of FAK Activity by Tetraspan Proteins: Potential Clinical Implications in Cancer.Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.The soy-derived peptide Lunasin inhibits invasive potential of melanoma initiating cellsFocal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion.Molecular and cellular impact of Psoriasin (S100A7) on the healing of human wounds.HGF/Met Signaling in Cancer Invasion: The Impact on Cytoskeleton Remodeling.Leucine-rich glioma inactivated 3: integrative analyses support its prognostic role in gliomaLoss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in miceIntegrin α2β1 in nonactivated conformation can induce focal adhesion kinase signalingMarine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insightsIntravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling.FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growthIdentification of FAK substrate peptides via colorimetric screening of a one-bead one-peptide combinatorial library.Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer.PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer.Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction.Novel Role of Src in Priming Pyk2 Phosphorylation.A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancersProtein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse.FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.The effect of soluble E-selectin on tumor progression and metastasis.
P2860
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P2860
FAK in cancer: mechanistic findings and clinical applications
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
FAK in cancer: mechanistic findings and clinical applications
@ast
FAK in cancer: mechanistic findings and clinical applications
@en
FAK in cancer: mechanistic findings and clinical applications
@nl
type
label
FAK in cancer: mechanistic findings and clinical applications
@ast
FAK in cancer: mechanistic findings and clinical applications
@en
FAK in cancer: mechanistic findings and clinical applications
@nl
prefLabel
FAK in cancer: mechanistic findings and clinical applications
@ast
FAK in cancer: mechanistic findings and clinical applications
@en
FAK in cancer: mechanistic findings and clinical applications
@nl
P2860
P3181
P356
P1476
FAK in cancer: mechanistic findings and clinical applications
@en
P2093
David D. Schlaepfer
Florian J. Sulzmaier
P2860
P2888
P304
P3181
P356
10.1038/NRC3792
P407
P577
2014-09-01T00:00:00Z
P6179
1032921892