Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease - Wikidata - wikimedia - TriplyDB

Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

http://www.wikidata.org/entity/Q27026599

about

Targeting innate immunity for neurodegenerative disorders of the central nervous system Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease in focal cerebral ischemic rats Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease Microglia-Induced Maladaptive Plasticity Can Be Modulated by Neuropeptides In Vivo Rodent models of neuroinflammation for Alzheimer's disease Stress-induced neuroinflammatory priming: A liability factor in the etiology of psychiatric disorders Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's Disease NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats Altered Brain Glucose Consumption in Cogan's Syndrome.Transcriptomic evidence of a para-inflammatory state in the middle aged lumbar spinal cord.Daily supplementation with GrandFusion® improves memory and learning in aged rats Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response.Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment.Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques.Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production.Microglia in the TBI brain: The good, the bad, and the dysregulated.Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease.CpG methylation differences between neurons and glia are highly conserved from mouse to human.Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba-1 or GFAP immunoreactivity following systemic immune challenge.A working model for the assessment of disruptions in social behavior among aged rats: The role of sex differences, social recognition, and sensorimotor processes Principal components derived from CSF inflammatory profiles predict outcome in survivors after severe traumatic brain injury Cognitive deficits develop 1month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge.Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury.Age-dependent differences in microglial responses to systemic inflammation are evident as early as middle age Tollip, an early regulator of the acute inflammatory response in the substantia nigra Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System.Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia?MicroRNAs: Roles in Regulating Neuroinflammation.Obesity Impacts Fever and Sickness Behavior During Acute Systemic Inflammation.Glial Na(+) -dependent ion transporters in pathophysiological conditions.Microglia in health and pain: impact of noxious early life events.Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders.Disordered APP metabolism and neurovasculature in trauma and aging: Combined risks for chronic neurodegenerative disorders.Aging leads to altered microglial function that reduces brain resiliency increasing vulnerability to neurodegenerative diseases.

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Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

http://www.wikidata.org/entity/Q27026599

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J.NEUROPHARM.2014.10.028

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Neuropharmacology

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Microglial priming and enhance ...... and neurodegenerative disease

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Diana M. Norden

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Jonathan P. Godbout

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Megan M. Muccigrosso

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P2860

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

The spectrum of disease in chronic traumatic encephalopathy

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

From inflammation to sickness and depression: when the immune system subjugates the brain

Animal models of traumatic brain injury

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Major depression following traumatic brain injury

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model

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neurodegeneration

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