about
Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivationAspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation.Aspirin-Triggered Resolvin D1-modified materials promote the accumulation of pro-regenerative immune cell subsets and enhance vascular remodeling.Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release.The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in ratsResolvins Decrease Oxidative Stress Mediated Macrophage and Epithelial Cell Interaction through Decreased Cytokine Secretion.Enhanced Resolution of Hyperoxic Acute Lung Injury as a result of Aspirin Triggered Resolvin D1 Treatment.Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway.Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury.Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses.17(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice.Resolvin D1 Dampens Pulmonary Inflammation and Promotes Clearance of Nontypeable Haemophilus influenzaeResolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion.AT-RvD1 Promotes Resolution of Inflammation in NOD/ShiLtJ mice.Aspirin-Triggered Resolvin D1 Inhibits TGF-β1-Induced EndMT through Increasing the Expression of Smad7 and Is Closely Related to Oxidative StressInhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models.Aspirin-triggered resolvin D1 reduces pneumococcal lung infection and inflammation in a viral and bacterial coinfection pneumonia model.Frontline Science: Aspirin-triggered resolvin D1 controls herpes simplex virus-induced corneal immunopathology.Effects of aspirin-triggered resolvin D1 on peripheral blood mononuclear cells from patients with Chagas' heart disease.AT-RvD1 combined with DEX is highly effective in treating TNF-α-mediated disruption of the salivary gland epitheliumAspirin-triggered resolvin D1 inhibits TGF-β1-induced EMT through the inhibition of the mTOR pathway by reducing the expression of PKM2 and is closely linked to oxidative stress.Resolvins RvD1 and 17(R)-RvD1 alleviate signs of inflammation in a rat model of endometriosis.Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline.AT-RvD1 modulates the activation of bronchial epithelial cells induced by lipopolysaccharide and Dermatophagoides pteronyssinus.Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury.Aspirin-Triggered Resolvin D1 Versus Dexamethasone in the Treatment of Sjögren's Syndrome-Like NOD/ShiLtJ Mice - A Pilot Study
P921
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description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
aspirin-triggered resolvin D1
@en
type
label
aspirin-triggered resolvin D1
@en
altLabel
AT-Resolvin D1
@en
AT-RvD1
@en
prefLabel
aspirin-triggered resolvin D1
@en
P592
P661
P662
P683
P2017
CC/C=C\C[C@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CCC(=O)O)O)O)O
P2063
LMFA04030005
P2067
376.224974
P233
CCC=CCC(C=CC=CC=CC=CC(C(CC=CCCC(=O)O)O)O)O
P234
1S/C22H32O5/c1-2-3-9-14-19(23) ...... -10+,16-11+/t19-,20-,21+/m1/s1
P235
OIWTWACQMDFHJG-BJEBZIPWSA-N
P274
P592
CHEMBL519495