about
sameAs
Tyrosine kinase inhibitors influence ABCG2 expression in EGFR-positive MDCK BCRP cells via the PI3K/Akt signaling pathway.G1 cell cycle arrest due to the inhibition of erbB family receptor tyrosine kinases does not require the retinoblastoma protein.Tyrosine kinase inhibitors. 14. Structure-activity relationships for methylamino-substituted derivatives of 4-[(3-bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase activityDissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells.Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway.Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor.An acute effect of neuregulin 1 beta to suppress alpha 7-containing nicotinic acetylcholine receptors in hippocampal interneurons.Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells.Growth inhibition of nasopharyngeal carcinoma cells by EGF receptor tyrosine kinase inhibitors
P921
Q39392579-D6A8E272-9F53-490B-A05B-5D65BBAD8850Q40486352-E1E50372-708B-4376-9BA4-AF4ECE837E10Q41056981-3C0867D4-43EC-45CB-B09D-47FC4163C7D9Q42805978-6AC7763E-15A9-4F4B-B8FA-EB712FE299C3Q42829479-E945C369-217F-482F-9095-FD837084E912Q42834569-08282F00-E70C-4A58-871D-A5820BDC5651Q48380938-00778C6F-411C-4822-93DA-563AF1A09CA9Q51252985-6EB62124-1F3A-4886-B9A1-080A1BA1C37FQ77881213-DCAB6885-79A8-4778-897F-1E17667FDE96
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
PD 158780
@en
type
label
PD 158780
@en
altLabel
AC1L1IRV
@en
N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine
@en
PD-158780
@en
PD158780
@en
prefLabel
PD 158780
@en
P592
P661
P662
P683
P2067
329.027608
P231
171179-06-9
P232
P233
CNC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br
P234
1S/C14H12BrN5/c1-16-13-6-11-12 ...... 2-8H,1H3,(H,16,17)(H,18,19,20)
P235
KFHMLBXBRCITHF-UHFFFAOYSA-N
P2566
100.209.086
P274
C₁₄H₁₂BrN₅
P3117
DTXSID20274443
P592
CHEMBL53753