about
Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis.Withanolide D, carrying the baton of Indian rasayana herb as a lead candidate of antileukemic agent in modern medicine.Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.Changes in morphological phenotypes and withanolide composition of Ri-transformed roots of Withania somnifera.Mode of action of Withaferin A and Withanolide DCytotoxic withanolides from Tubocapsicum anomalum
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
withanolide D
@en
type
label
withanolide D
@en
prefLabel
withanolide D
@en
P661
P662
P665
P683
P1579
P2017
CC1=C(C(=O)O[C@H](C1)[C@@](C)( ...... ]4(C(=O)C=C[C@@H]6O)C)O5)C)O)C
P2064
P2067
470.266839
P231
30655-48-2
P233
CC1=C(C(=O)OC(C1)C(C)(C2CCC3C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)O)C
P234
1S/C28H38O6/c1-14-12-22(33-24( ...... ,22+,23+,25-,26-,27+,28+/m0/s1
P235
SASUFNRGCZMRFD-JCUIILOWSA-N