about
Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases.Methionine AminoPeptidase Type-2 Inhibitors Targeting Angiogenesis.Advanced Chemoembolization by Anti-angiogenic Calcium-Phosphate Ceramic Microspheres Targeting the Vascular Heterogeneity of Cancer Xenografts.Frequent administration of angiogenesis inhibitor TNP-470 (AGM-1470) at an optimal biological dose inhibits tumor growth and metastasis of metastatic human transitional cell carcinoma in the urinary bladder.Primary study in experimental antiangiogenic therapy of nasopharyngeal carcinoma with AGM-1470 (TNP-470).TNP-470 (AGM-1470): mechanisms of action and early clinical development.The angiogenic inhibitor TNP-470 decreases caloric intake and weight gain in high-fat fed mice.Effect of TNP-470 (AGM-1470) on the growth of rat rhabdomyosarcoma tumors of different sizes.Pharmacokinetics and metabolism of O-(chloroacetyl-carbamoyl) fumagillol (TNP-470, AGM-1470) in rhesus monkeysThe angiogenesis inhibitor TNP-470 (AGM-1470) improves long-term survival of rats with liver metastasisAn angiogenesis inhibitor TNP-470 (AGM-1470) suppresses vascular smooth muscle cell proliferation in experimental rat aortotomy models
P921
Q24810481-5552401D-05C4-470B-8765-9B54BA0B8D98Q38586716-D6B94B46-E9BA-474F-88A9-DD310484D8E3Q38845296-50D5BED3-45CB-4420-9984-730B38331242Q40718812-37FB2CE9-9621-4A4A-8365-AA960D2E1B20Q40983639-F008F41E-0975-481B-B40D-2BD9BE9639EFQ41372753-34B75D56-2D2E-4379-9DAE-CBB702E88CCFQ42055222-98C0FC90-146F-4277-ADCD-D983BD8DA66EQ43567474-99773CF1-E0CD-43C9-B3F7-7B1946AA7F02Q71046948-650C9F53-BC0A-4A3A-820B-FA2D1465E37EQ71530133-B417893B-A1E4-4A29-89B9-FEA071C8EC64Q81451534-4B3F0712-B400-496D-AAFA-BE133BFA6D17
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
tnp-470
@en
type
label
tnp-470
@en
altLabel
AGM-1470
@en
Agm 1470
@en
DRG-0148
@en
O-(chloroacetylcarbamoyl)fumagillol
@en
O-chloroacetylcarbamoylfumagillol
@en
TNP 470
@en
TNP-470
@en
prefLabel
tnp-470
@en
P486
P592
P661
P662
P683
P1579
P2017
CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)NC(=O)CCl)OC)C
P2067
401.160515
P231
129298-91-5
P232
P233
CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)NC(=O)CCl)OC)C
P234
1S/C19H28ClNO6/c1-11(2)5-6-13- ...... t12-,13-,15-,16-,18+,19+/m1/s1
P235
MSHZHSPISPJWHW-PVDLLORBSA-N
P2566
100.189.666
P274
C₁₉H₂₈ClNO₆
P2840
P3117
DTXSID0041141
P486
P592
CHEMBL424278
P652
X47GR46481