about
Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancerFatal outcome of posterior "reversible" encephalopathy syndrome in metastatic colorectal carcinoma after irinotecan and fluoropyrimidine chemotherapy regimen.Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride.Development and characterization of pH responsive polymeric nanoparticles of SN-38 for colon cancer.Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, with irinotecan hydrochloride on human colorectal and gastric cancer xenografts.Long-term survival in small-cell carcinoma of the endometrium with liver and brain metastases.Biophysical and molecular docking insight into interaction mechanism and thermal stability of human serum albumin isoforms with a semi-synthetic water-soluble camptothecin analog irinotecan hydrochloride.Somatic p.T771R KDR (VEGFR2) Mutation Arising in a Sporadic Angioma During Ramucirumab Therapy.Vaginal carcinoma in a young woman who underwent fertility-sparing treatment involving chemotherapy and conservative surgery.Antitumor effects with apoptotic death in human promyelocytic leukemia HL-60 cells and suppression of leukemia xenograft tumor growth by irinotecan HCl[Pharmacokinetics of SN-38 in rats and tissue distribution of 7-ethyl-10-hydroxycamptothecin in mice after intravenous injection of irinotecan hydrochloride nanoparticles]
P921
Q26775949-164DDFAB-FF46-4171-AEB5-1570CD524387Q34084877-E2379BAC-FCE8-484D-9F2D-1967C213195EQ35829622-7428D37F-34FD-4B14-A902-1EAE9D2C4649Q38821844-119DB646-FC50-4CD9-B7F9-A567F1D78D36Q38902330-2166CF87-829C-42B2-88D7-8730BE8F9633Q40559800-E019A79C-8318-467E-B1DC-AE2B094CCCE6Q46548051-F2F68921-6684-407E-A751-ADAC237A6E63Q50929651-58BD724F-8C74-4100-A4BD-1E958E5DD6A5Q53667557-A3D75CC3-5DEC-4AF1-A9CB-DDEAC97F31BFQ57017738-616DC448-BD80-4169-98EE-49E1584CBA49Q85333729-816F045A-D41B-460B-A2A7-10E6A60C147B
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
irinotecan hydrochloride
@en
type
label
irinotecan hydrochloride
@en
altLabel
7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxy camptothecin hydrochloride
@en
CPT 11
@en
CPT-11
@en
Camptothecin 11 hydrochloride
@en
Irinotecan HCl
@en
Irinotecan hydrochloride
@en
U 101440E
@en
irinotecan hydrochloride anhydrous
@en
irinotecan monohydrochloride
@en
prefLabel
irinotecan hydrochloride
@en
P592
P661
P662
P683
P1579
P2017
CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
P2067
P231
100286-90-6
P232
P233
CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
P234
1S/C33H38N4O6.ClH/c1-3-22-23-1 ...... ,18-19H2,1-2H3;1H/t33-;/m0./s1
P235
GURKHSYORGJETM-WAQYZQTGSA-N
P2566
100.127.784
P274
C₃₃H₃₉ClN₄O₆
P3117
DTXSID6045953
P592
CHEMBL541887
P652
06X131E4OE