Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool - Wikidata - wikimedia - TriplyDB

Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool

Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool

http://www.wikidata.org/entity/Q27312139

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Optogenetics for neurodegenerative diseases.Aberrant Activity in Degenerated Retinas Revealed by Electrical Imaging Neurobiological Insights from mGlu Receptor Allosteric Modulation.Optogenetics: 10 years of microbial opsins in neuroscience.Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity.Biophysical Properties of Optogenetic Tools and Their Application for Vision Restoration Approaches Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuits Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches Retinal Remodeling: Concerns, Emerging Remedies and Future Prospects.Let There Be Light: Gene and Cell Therapy for Blindness.Red-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina.Chronic activation of the D156A point mutant of Channelrhodopsin-2 signals apoptotic cell death: the good and the bad Present Molecular Limitations of ON-Bipolar Cell Targeted Gene Therapy.Photoreceptor engineering Natural Resources for Optogenetic Tools.Overview on Research and Clinical Applications of Optogenetics.Subretinal electrical stimulation reveals intact network activity in the blind mouse retina.A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.Optogenetic toolkit for precise control of calcium signaling.Integration of optogenetics with complementary methodologies in systems neuroscience.Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina.Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina.Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina.Restoration of Vision with Ectopic Expression of Human Rod Opsin.Dampening Spontaneous Activity Improves the Light Sensitivity and Spatial Acuity of Optogenetic Retinal Prosthetic Responses.Inference of neuronal functional circuitry with spike-triggered non-negative matrix factorization.Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness.Photopharmacological control of bipolar cells restores visual function in blind mice Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.Blockade of pathological retinal ganglion cell hyperactivity improves optogenetically evoked light responses in rd1 mice.Spotlight on pain: optogenetic approaches for interrogating somatosensory circuits.Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling.Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics.A Robust Optomotor Assay for Assessing the Efficacy of Optogenetic Tools for Vision Restoration.New Experimental Models of Retinal Degeneration for Screening Molecular Photochromic Ion Channel Blockers.Optical functionalization of human Class A orphan G-protein-coupled receptors.Innovative Optogenetic Strategies for Vision Restoration

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Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool

http://www.wikidata.org/entity/Q27312139

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2015 nî lūn-bûn

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2015 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2015 թվականի մայիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Restoring the ON Switch in Bli ...... Cell-Tailored Optogenetic Tool

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Restoring the ON Switch in Bli ...... Cell-Tailored Optogenetic Tool

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Restoring the ON Switch in Bli ...... Cell-Tailored Optogenetic Tool

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Restoring the ON Switch in Bli ...... Cell-Tailored Optogenetic Tool

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Restoring the ON Switch in Bli ...... Cell-Tailored Optogenetic Tool

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JOURNAL.PBIO.1002143

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Restoring the ON Switch in Bli ...... Cell-Tailored Optogenetic Tool

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Justyna Pielecka-Fortuna

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Siegrid Löwel

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Sonja Kleinlogel

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Melanopsin contributions to irradiance coding in the thalamo-cortical visual system

Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration

Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity

Immunology of AAV-Mediated Gene Transfer in the Eye

Retinal degeneration mutants in the mouse

Phototransduction by retinal ganglion cells that set the circadian clock

Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN

Effect of gene therapy on visual function in Leber's congenital amaurosis

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13

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Michiel van Wyk

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2015-05-07T00:00:00Z

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