Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
about
Current Landscape of Antiviral Drug DiscoveryInvestigating the Role of Large-Scale Domain Dynamics in Protein-Protein InteractionsThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignComparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching EndonucleasesInfluenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.X-ray structure and activities of an essential Mononegavirales L-protein domainInfluenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.Structural insights into reptarenavirus cap-snatching machinery.New Insight into Metal Ion-Driven Catalysis of Nucleic Acids by Influenza PA-NterStructural Biology of the Arterivirus nsp11 Endoribonucleases.Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors.Polycistronic Expression of the Influenza A Virus RNA-Dependent RNA Polymerase by Using the Thosea asigna Virus 2A-Like Self-Processing Sequence.Role of the PB2 627 Domain in Influenza A Virus Polymerase FunctionAnnotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis.Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA.The role of the priming loop in influenza A virus RNA synthesis.Genome-wide analysis of influenza viral RNA and nucleoprotein association.Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit.Structural characterization of recombinant IAV polymerase reveals a stable complex between viral PA-PB1 heterodimer and host RanBP5.RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II.Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.Initiation, elongation and realignment during influenza virus mRNA synthesis.A Mechanism for Priming and Realignment during Influenza A Virus Replication.The Battle of RNA Synthesis: Virus versus Host.MultiBac: from protein complex structures to synthetic viral nanosystems.Amino acid substitutions affecting aspartic acid 605 and valine 606 decrease the interaction strength between the influenza virus RNA polymerase PB2 '627' domain and the viral nucleoprotein.Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution.Structural and Functional Motifs in Influenza Virus RNAs.A Mechanism for the Activation of the Influenza Virus Transcriptase.Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza PolymeraseThe Surface-Exposed PA-Loop of the Influenza A Virus Polymerase Is Required for Viral Genome ReplicationTemperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine
P2860
Q26766639-FBC7A69E-4405-43EB-A30C-F1D0C0D60B8AQ28070759-ADC46C87-3D8D-4A53-9170-DE689874F65AQ28071809-37CACC99-D566-483B-A23A-E6BAE446E22DQ28550279-7E04E43C-62BA-400F-A1D8-2BF584486740Q30791826-89C18B44-96FE-48C0-922C-4D44C396DE6DQ34501048-BF642664-C5D3-43AE-B371-7A19E2502399Q35879897-485208AE-24B2-4E48-A7D4-E3FD355A348DQ36372058-A8910316-8198-455B-A7BA-0ADDC22556FFQ37003230-E135B4C8-3D7E-44CA-AF4B-B4AB8AD28E71Q37512934-06F05F8C-1248-466F-90C2-948499F0EBD6Q38642237-4A6B79C5-8FC8-4D14-B088-561CB98FE4C1Q38832421-9033F5DF-D9B1-4E92-95E2-503C20BD62FDQ38998940-D373A385-CA7E-4C10-B0C6-303450A4186AQ39226164-6EB592A4-C6D4-488E-B82D-E04B6BA0C894Q39330639-7FBFCCB5-5E56-4A95-80DB-EBB810661FCDQ39442923-0D94EC73-22D4-4052-9F8A-E83F863FDE48Q40040753-798F4F67-D19F-4B4D-8E85-094BA1596FFAQ40071053-D7160758-CD18-48BA-B232-A4D25A79C034Q40370553-5F955469-06AC-4A98-9196-95AECCAF8869Q40705551-FA4D633F-B435-49FC-B5AD-7D18526F50DDQ45323667-003E4FEE-B5D3-4435-A9E4-50C9CE4AB550Q45324803-8C98831A-6CF5-4367-9A03-7037ACCA640DQ45325109-AFB053BB-9311-4F40-A80C-1DE79119BA4DQ45325752-F6BB7864-0004-4BEF-B9FA-49ADF0D24C0DQ46885704-10F10350-8C37-468E-8D2E-1FE617F4CE61Q47553044-F19FDBB5-6A89-4946-9A54-268F0A2D602AQ47569878-57111BA9-9DF4-452B-8E85-9FE89CCD1909Q50034148-CFA4584F-7923-4747-AD10-20FC2AED1C9BQ52322904-2E7AF199-7646-4762-8899-9A3ECE5FAF7AQ55420805-10D36E20-417D-49EF-BA6D-584AFFB59C23Q57018065-FBD2AA41-16AC-444D-92BC-99F1E1864FBDQ57094150-450C1FD3-9627-45D9-874E-F7DCB61A67D9Q57466491-E592B9DA-226D-44F2-89DA-4A6F1C9D90C1
P2860
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
description
2015 nî lūn-bûn
@nan
2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus
@nl
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@ast
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@en
type
label
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus
@nl
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@ast
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@en
prefLabel
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus
@nl
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@ast
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
@en
P2093
Clemens Vonrhein
Frank T Vreede
Gérard Bricogne
Jonathan M Grimes
Robert P Rambo
P2860
P2888
P304
P3181
P356
10.1038/NATURE15525
P407
P577
2015-10-26T00:00:00Z
P6179
1049518165