Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo - Wikidata - wikimedia - TriplyDB

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

http://www.wikidata.org/entity/Q27318346

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The adenovirus genome contributes to the structural stability of the virion TLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetes A capsid-encoded PPxY-motif facilitates adenovirus entry Sheep lung segmental delivery strategy demonstrates adenovirus priming of local lung responses to bacterial LPS and the role of elafin as a response modulator Adenovirus membrane penetration: Tickling the tail of a sleeping dragon Development of adenoviral vector-based mucosal vaccine against influenza.Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes Viral capsid is a pathogen-associated molecular pattern in adenovirus keratitis Evaluation of the HC-04 cell line as an in vitro model for mechanistic assessment of changes in hepatic cytochrome P450 3A during adenovirus infection.The early activation of CD8+ T cells is dependent on type I IFN signaling following intramuscular vaccination of adenovirus vector.Direct evidence from single-cell analysis that human {alpha}-defensins block adenovirus uncoating to neutralize infection.Conventional but not plasmacytoid dendritic cells foster the systemic virus-induced type I IFN response needed for efficient CD8 T cell priming.Recognition of virus infection and innate host responses to viral gene therapy vectors.A potential role of the JNK pathway in hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated injury in the developing murine lung.Induction of type I interferon by adenovirus-encoded small RNAs.Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine.Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity.The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine.A dual character of flavonoids in influenza A virus replication and spread through modulating cell-autonomous immunity by MAPK signaling pathways.Chemical induction of unfolded protein response enhances cancer cell killing through lytic virus infection.Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells.Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics.Implications of the innate immune response to adenovirus and adenoviral vectors.Identification of Toll-like receptor 9 as parapoxvirus ovis-sensing receptor in plasmacytoid dendritic cells Virus infection recognition and early innate responses to non-enveloped viral vectors.The role of endosomal escape and mitogen-activated protein kinases in adenoviral activation of the innate immune response.STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.Baicalin Protects Keratinocytes from Toll-like Receptor-4 Mediated DNA Damage and Inflammation Following Ultraviolet Irradiation.Type I interferons: diversity of sources, production pathways and effects on immune responses.Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity.Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis Genetic reconstitution of the human adenovirus type 2 temperature-sensitive 1 mutant defective in endosomal escape.A new link between virus cell entry and inflammation: adenovirus interaction with integrins induces specific proinflammatory responses.Innate immunity to adenovirus.Viral weapons of membrane destruction: variable modes of membrane penetration by non-enveloped viruses.

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

http://www.wikidata.org/entity/Q27318346

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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type

label

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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prefLabel

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

@en

Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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JOURNAL.PPAT.1000208

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

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Anne Krug

http://www.w3.org/2001/XMLSchema#string

Bernd Hildenbrand

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Christian Bogdan

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György Fejer

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Jan Liese

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Lisa Drechsel

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Marina A Freudenberg

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Nicola Imelli

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Simone Keck

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Ulrike Schleicher

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P2860

Direct suppression of Stat1 function during adenoviral infection

Functional role of type I and type II interferons in antiviral defense

A Toll-like receptor recognizes bacterial DNA

Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

5'-Triphosphate RNA is the ligand for RIG-I

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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e1000208

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