Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells
about
Deciphering the roles of phosphoinositide lipids in phagolysosome biogenesisPtdIns(4,5)P₂ and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance.Differential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagyRegulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesisPhagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans.PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal modelsVertebrate epidermal cells are broad-specificity phagocytes that clear sensory axon debrisRab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophagesPI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis.PtdIns5P: news and views of its appearance, disappearance and deeds.The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.Components of the Engulfment Machinery Have Distinct Roles in Corpse ProcessingPlentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).You are what you eat: multifaceted functions of autophagy during C. elegans development.Classes of phosphoinositide 3-kinases at a glance.Tethering complexes in the endocytic pathway: CORVET and HOPS.PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3-phosphate dynamics.C. elegans midbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagyMonitoring the clearance of apoptotic and necrotic cells in the nematode Caenorhabditis elegans.Programmed Cell Death During Caenorhabditis elegans DevelopmentAutophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans.Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation.LC3-Associated Phagocytosis and Inflammation.The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.Dissecting Phagocytic Removal of Apoptotic Cells in Caenorhabditis elegans.Analysis of Phagocytosis in the Drosophila Ovary.The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cellsC. elegans RAB-35: Dual roles in apoptotic cell clearanceMultiple Aspects of PIP2 Involvement in Gametogenesis
P2860
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P248
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P2860
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@ast
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@en
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@nl
type
label
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@ast
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@en
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@nl
prefLabel
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@ast
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@en
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@nl
P2093
P2860
P3181
P1433
P1476
Two PI 3-kinases and one PI 3- ...... degradation of apoptotic cells
@en
P2093
Timothy R Mahoney
Zheng Zhou
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001245
P407
P577
2012-01-17T00:00:00Z