Investigating the structure and dynamics of the PIK3CA wild-type and H1047R oncogenic mutant

Investigating the structure and dynamics of the PIK3CA wild-type and H1047R oncogenic mutant

Item
http://www.wikidata.org/entity/Q27320874
Deciphering the impact of somatic mutations in exon 20 and exon 9 of PIK3CA gene in breast tumors among Indian women through molecular dynamics approach.Next generation sequencing of the nidus of early (adenosquamous proliferation rich) radial sclerosing lesions of the breast reveals evidence for a neoplastic precursor lesion.Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α.Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterationsThe Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal CarcinomasHereditary breast and ovarian cancer: new genes in confined pathways.Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase modelGenes with mutation significance were highly associated with the clinical pattern of patients with breast cancer.Molecular Dynamics Simulations and Dynamic Network Analysis Reveal the Allosteric Unbinding of Monobody to H-Ras Triggered by R135K Mutation.Actionable mutations in canine hemangiosarcoma.Molecular Dynamics Simulations to Investigate the Binding Mode of the Natural Product Liphagal with Phosphoinositide 3-Kinase α.Experimental verification of a predicted novel microRNA located in human PIK3CA gene with a potential oncogenic function in colorectal cancer.Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.Insights into the mechanism of the PIK3CA E545K activating mutation using MD simulations
P2860

Investigating the structure and dynamics of the PIK3CA wild-type and H1047R oncogenic mutant

Item
http://www.wikidata.org/entity/Q27320874
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Investigating the structure an ...... pe and H1047R oncogenic mutant
@ast
Investigating the structure an ...... pe and H1047R oncogenic mutant
@en
Investigating the structure an ...... pe and H1047R oncogenic mutant
@nl
type
label
Investigating the structure an ...... pe and H1047R oncogenic mutant
@ast
Investigating the structure an ...... pe and H1047R oncogenic mutant
@en
Investigating the structure an ...... pe and H1047R oncogenic mutant
@nl
prefLabel
Investigating the structure an ...... pe and H1047R oncogenic mutant
@ast
Investigating the structure an ...... pe and H1047R oncogenic mutant
@en
Investigating the structure an ...... pe and H1047R oncogenic mutant
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P3181
P356
P1433
P1476
Investigating the structure an ...... pe and H1047R oncogenic mutant
@en
P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PCBI.1003895
P407
P433
P478
P50
P577
P5875
P698
P932