Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis

Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis

Item
http://www.wikidata.org/entity/Q27321405
An ordered water channel in Staphylococcus aureus FabI: unraveling the mechanism of substrate recognition and reduction.Experimental phasing using zinc anomalous scatteringStructural Basis for the Recognition of Mycolic Acid Precursors by KasA, a Condensing Enzyme and Drug Target from Mycobacterium TuberculosisA structural and energetic model for the slow-onset inhibition of the Mycobacterium tuberculosis enoyl-ACP reductase InhA.Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpartCo-factor binding confers substrate specificity to xylose reductase from Debaryomyces hansenii.Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitorQuality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.A unique peptide deformylase platform to rationally design and challenge novel active compounds.Proteome-wide analysis of the amino terminal status of Escherichia coli proteins at the steady-state and upon deformylation inhibition.The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation.Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes.Conformational selection and induced changes along the catalytic cycle of Escherichia coli dihydrofolate reductase.
P2860

Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis

Item
http://www.wikidata.org/entity/Q27321405
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
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name
Trapping conformational states ...... nduced fit on enzyme catalysis
@ast
Trapping conformational states ...... nduced fit on enzyme catalysis
@en
Trapping conformational states ...... nduced fit on enzyme catalysis
@nl
type
label
Trapping conformational states ...... nduced fit on enzyme catalysis
@ast
Trapping conformational states ...... nduced fit on enzyme catalysis
@en
Trapping conformational states ...... nduced fit on enzyme catalysis
@nl
altLabel
Trapping Conformational States ...... nduced Fit on Enzyme Catalysis
@en
prefLabel
Trapping conformational states ...... nduced fit on enzyme catalysis
@ast
Trapping conformational states ...... nduced fit on enzyme catalysis
@en
Trapping conformational states ...... nduced fit on enzyme catalysis
@nl
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Trapping conformational states ...... nduced fit on enzyme catalysis
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P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PBIO.1001066
P407
P433
P478
P50
P577
P5875
P698
P921
P932