Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour - Wikidata - wikimedia - TriplyDB

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour

http://www.wikidata.org/entity/Q27321808

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Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure Inhibitory signalling to the Arp2/3 complex steers cell migration Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes A comparison of computational models for eukaryotic cell shape and motility New paradigms in the establishment and maintenance of gradients during directed cell migration An excitable cortex and memory model successfully predicts new pseudopod dynamics Three-dimensional numerical model of cell morphology during migration in multi-signaling substrates Crawling and Gliding: A Computational Model for Shape-Driven Cell Migration Geometry-Driven Polarity in Motile Amoeboid Cells Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells Oscillatory behavior of neutrophils under opposing chemoattractant gradients supports a winner-take-all mechanism Image based validation of dynamical models for cell reorientation.Linking morphodynamics and directional persistence of T lymphocyte migration Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of Chemotaxis Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration Mathematical modeling of eukaryotic cell migration: insights beyond experiments Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion The neutrophil's eye-view: inference and visualisation of the chemoattractant field driving cell chemotaxis in vivo.Distinct cell shapes determine accurate chemotaxis Microtubules stabilize cell polarity by localizing rear signals.The directional response of chemotactic cells depends on a balance between cytoskeletal architecture and the external gradient.Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments.Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.Biogenesis of the posterior pole is mediated by the exosome/microvesicle protein-sorting pathway.Biased excitable networks: how cells direct motion in response to gradients.A critical-like collective state leads to long-range cell communication in Dictyostelium discoideum aggregation.Identifying network motifs that buffer front-to-back signaling in polarized neutrophils.Excitable behavior in amoeboid chemotaxis.A review of models of fluctuating protrusion and retraction patterns at the leading edge of motile cells.Envisioning migration: mathematics in both experimental analysis and modeling of cell behavior.Molecular players in neutrophil chemotaxis--focus on PI3K and small GTPases.Self-organization of protrusions and polarity during eukaryotic chemotaxis.Review of cellular mechanotransduction on micropost substrates.Feedback regulation between plasma membrane tension and membrane-bending proteins organizes cell polarity during leading edge formation.Progress and perspectives in signal transduction, actin dynamics, and movement at the cell and tissue level: lessons from Dictyostelium The Arp2/3 inhibitory protein Arpin is dispensable for chemotaxis.Non-Brownian dynamics and strategy of amoeboid cell locomotion.Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration.Local modulation of chemoattractant concentrations by single cells: dissection using a bulk-surface computational model

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Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour

http://www.wikidata.org/entity/Q27321808

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2011 nî lūn-bûn

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Chemotaxis: a feedback-based c ...... aspects of real cell behaviour

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JOURNAL.PBIO.1000618

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Chemotaxis: a feedback-based c ...... aspects of real cell behaviour

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Douwe M Veltman

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John A Mackenzie

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Matthew P Neilson

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Peter J M van Haastert

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Robert H Insall

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Steven D Webb

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P2860

Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration

Persistent cell motion in the absence of external signals: a search strategy for eukaryotic cells

Emergence of large-scale cell morphology and movement from local actin filament growth dynamics

An actin-based wave generator organizes cell motility

Navigation of chemotactic cells by parallel signaling to pseudopod persistence and orientation

The ordered extension of pseudopodia by amoeboid cells in the absence of external cues

Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.

Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in dictyostelium cells.

Calpain regulates neutrophil chemotaxis.

Exploring the control circuit of cell migration by mathematical modeling.

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