Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1 - Wikidata - wikimedia - TriplyDB

Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1

Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1

http://www.wikidata.org/entity/Q27334560

about

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.Intermittent activation of notch signaling promotes bone formation.Adipose-derived stem cells: a review of signaling networks governing cell fate and regenerative potential in the context of craniofacial and long bone skeletal repair.NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine.Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation Loss of osteoblast Runx3 produces severe congenital osteopenia Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age.Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption.Development of the endochondral skeleton Notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance NOTCH signaling in skeletal progenitors is critical for fracture repair.Notch Signaling and the Skeleton.HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in mice RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival Isolation, characterization, and molecular regulation of muscle stem cells.Notch signaling in skeletal stem cells.Notch signaling and bone remodeling.Notch1 maintains dormancy of olfactory horizontal basal cells, a reserve neural stem cell.The roles of signaling pathways in bone repair and regeneration.Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism.Hairy and Enhancer of Split-Related With YRPW Motif-Like (HeyL) Is Dispensable for Bone Remodeling in Mice.Sustained Notch2 signaling in osteoblasts, but not in osteoclasts, is linked to osteopenia in a mouse model of Hajdu-Cheney syndrome.Stem cell niche-specific Ebf3 maintains the bone marrow cavity.The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.

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P2860

Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1

http://www.wikidata.org/entity/Q27334560

description

2012 nî lūn-bûn

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2012 թուականին հրատարակուած գիտական յօդուած

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2012 թվականին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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type

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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JOURNAL.PGEN.1002577

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Physiological notch signaling ...... Pjk and Hey upstream of NFATc1

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Cornelia Wiese

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Courtney M Karner

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Fanxin Long

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Jianquan Chen

http://www.w3.org/2001/XMLSchema#string

Joohyun Lim

http://www.w3.org/2001/XMLSchema#string

Julia Heisig

http://www.w3.org/2001/XMLSchema#string

Seung-Yon Lee

http://www.w3.org/2001/XMLSchema#string

Xiaolin Tu

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis

Mutations in NOTCH1 cause aortic valve disease

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

Ligand-independent traffic of Notch buffers activated Armadillo in Drosophila

Notch signaling: cell fate control and signal integration in development

HES and HERP families: multiple effectors of the Notch signaling pathway

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e1002577

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scholarly article

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4464181

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10.1371/JOURNAL.PGEN.1002577

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3

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Manfred Gessler

Kameswaran Surendran

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2012-03-22T00:00:00Z

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223137342

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22457635

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3310726

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