Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity
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Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR PathwaydsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effectsInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseRIG-I in RNA virus recognitionCharacterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging AlphavirusesZika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic CellsThe Influenza A Virus Genotype Determines the Antiviral Function of NF-κBA Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection.Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activationRIG-I ATPase activity and discrimination of self-RNA versus non-self-RNA.Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors.Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon InductionAntiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I AgonistsEnhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as AdjuvantReversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.Molecular and genetic inflammation networks in major human diseases.Regulation of mitochondrial antiviral signaling (MAVS) expression and signaling by the mitochondria-associated endoplasmic reticulum membrane (MAM) protein Gp78.Targeting host factors to treat West Nile and dengue viral infections.Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand.Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response.Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors.Systems biology unravels interferon responses to respiratory virus infections.Antiviral strategies against influenza virus: towards new therapeutic approaches.Broad-spectrum antiviral agents.Synthetic agonists of NOD-like, RIG-I-like, and C-type lectin receptors for probing the inflammatory immune response.RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection.Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity.RIG-I and IL-6 are negative-feedback regulators of STING induced by double-stranded DNA.Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense.RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.The virulence factor PA protein of highly pathogenic H5N1 avian influenza virus inhibits NF-κB transcription in vitro.RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production.RIGulation of STING expression: at the crossroads of viral RNA and DNA sensing pathways.A minimal RNA ligand for potent RIG-I activation in living mice.Cytoplasmic Translocation of Nucleolar Protein NOP53 Promotes Viral Replication by Suppressing Host Defense.RIG-I-Like Receptors as Novel Targets for Pan-Antivirals and Vaccine Adjuvants Against Emerging and Re-Emerging Viral Infections.
P2860
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P2860
Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
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Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@en
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
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Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@ast
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@en
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@nl
prefLabel
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@ast
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@en
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@nl
P2093
P2860
P50
P1433
P1476
Systems analysis of a RIG-I ag ...... nhibition of virus infectivity
@en
P2093
Alain Lamarre
Andrew Smith
Elias K Haddad
Erin I Lafferty
Khader Ghneim
Marie-Line Goulet
Marilene Paquet
Mark Cameron
Meztli Arguello
Peter Wilkinson
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003298
P407
P577
2013-01-01T00:00:00Z