Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET
about
Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.A Pluridimensional View of Biased Agonism.Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosisInhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.Functional New World monkey oxytocin forms elicit an altered signaling profile and promotes parental care in rats.GPCR Signaling and Trafficking: The Long and Short of It.Endocrinology and the brain: corticotropin-releasing hormone signaling.A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.Biased signalling: from simple switches to allosteric microprocessors.Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins.Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches.Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.Overview of the detection methods for equilibrium dissociation constant KD of drug-receptor interaction.Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes
P2860
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P2860
Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET
description
2016 nî lūn-bûn
@nan
2016 թուականին հրատարակուած գիտական յօդուած
@hyw
2016 թվականին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@ast
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@en
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@nl
type
label
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@ast
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@en
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@nl
prefLabel
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@ast
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@en
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@nl
P2093
P2860
P50
P3181
P356
P1476
Monitoring G protein-coupled r ...... using enhanced bystander BRET
@en
P2093
Christian Le Gouill
Etienne Khoury
Mideum Song
Mireille Hogue
Stéphane A Laporte
Viktoria Lukashova
Yoon Namkung
P2860
P2888
P3181
P356
10.1038/NCOMMS12178
P407
P577
2016-01-01T00:00:00Z
P6179
1037867520