Predisposition to cancer caused by genetic and functional defects of mammalian Atad5 - Wikidata - wikimedia - TriplyDB

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

http://www.wikidata.org/entity/Q27336379

about

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.ATAD5 deficiency decreases B cell division and Igh recombination A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A Identification of six new susceptibility loci for invasive epithelial ovarian cancer.R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants Detecting false-positive signals in exome sequencing High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma.ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin.The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?Emerging genotype-phenotype relationships in patients with large NF1 deletions.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Review: The lord of the rings: Structure and mechanism of the sliding clamp loader.Homologous recombination maintenance of genome integrity during DNA damage tolerance.Control of Genome Integrity by RFC Complexes; Conductors of PCNA Loading onto and Unloading from Chromatin during DNA Replication.Alternative replication factor C protein, Elg1, maintains chromosome stability by regulating PCNA levels on chromatin.Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development.Regulation of Elg1 activity by phosphorylation.Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation.Genetic and physical interactions between the yeast ELG1 gene and orthologs of the Fanconi anemia pathway.PCNA Retention on DNA into G2/M Phase Causes Genome Instability in Cells Lacking Elg1.ATAD2 in cancer: a pharmacologically challenging but tractable target.

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Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

http://www.wikidata.org/entity/Q27336379

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@ast

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@en

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@nl

type

label

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@ast

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@en

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@nl

prefLabel

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@ast

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@en

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

@nl

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JOURNAL.PGEN.1002245

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Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

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Abdel Elkahloun

http://www.w3.org/2001/XMLSchema#string

Andrew K Godwin

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Bhavesh Borate

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Charles Vinson

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Christin L Hanigan

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Dae-Sik Lim

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Daphne W Bell

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Dennis C Sgroi

http://www.w3.org/2001/XMLSchema#string

Gabriel Renaud

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Gene Elliot

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P2860

hRAD30 mutations in the variant form of xeroderma pigmentosum

DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation

An integrated genomic analysis of human glioblastoma multiforme

Base-calling of automated sequencer traces using phred. II. Error probabilities

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

Consed: a graphical tool for sequence finishing

The genomic landscapes of human breast and colorectal cancers

Elg1 forms an alternative RFC complex important for DNA replication and genome integrity

The N- and C-termini of Elg1 contribute to the maintenance of genome stability.

ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C

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e1002245

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scholarly article

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1830656

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10.1371/JOURNAL.PGEN.1002245

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8

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7

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James C Mullikin

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2011-08-01T00:00:00Z

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51626997

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21901109

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3161924

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