Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
about
Involvement of aspartoacylase in tremor expression in rats.Localisation of N-acetylaspartate in oligodendrocytes/myelinA new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelinationA single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease.Glial promoter selectivity following AAV-delivery to the immature brain.Increasing N-acetylaspartate in the Brain during Postnatal Myelination Does Not Cause the CNS Pathologies of Canavan Disease.Loss of central auditory processing in a mouse model of Canavan disease.Making the White Matter Matters: Progress in Understanding Canavan's Disease and Therapeutic Interventions Through Eight Decades.rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System.Gene Therapy for the Treatment of Neurological Disorders: Metabolic Disorders.Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan LeukodystrophyA thematic review of scientific and family interests in Canavan Disease: where are the developmentalists?Advances and pitfalls of cell therapy in metabolic leukodystrophies.Identification of quantitative trait transcripts for growth traits in the large scales of liver and muscle samples.Recombinant Human Myelin-Associated Glycoprotein Promoter Drives Selective AAV-Mediated Transgene Expression in Oligodendrocytes.Close-field electroporation gene delivery using the cochlear implant electrode array enhances the bionic ear.Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain.
P2860
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P2860
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
description
2011 nî lūn-bûn
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@ast
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@en
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@nl
type
label
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@ast
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@en
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@nl
prefLabel
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@ast
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@en
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@nl
P2093
P2860
P3181
P1433
P1476
Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease
@en
P2093
Dmitri Tkachev
Matthias Klugmann
Nadine Mersmann
Philipp Thomas Röth
Ruth Jelinek
Sabine Rühle
Torben Ruhwedel
Wolfgang Weber-Fahr
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0020336
P407
P577
2011-01-01T00:00:00Z