Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells
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Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand RecognitionTargeting dendritic cell function during systemic autoimmunity to restore toleranceContribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosusAugmenting antitumor immune responses with epigenetic modifying agents.Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming.Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6.Feasibility of up-regulating CD4(+)CD25(+) Tregs by IFN-γ in myasthenia gravis patients.Dysregulated co-stimulatory molecule expression in a Sjögren's syndrome mouse model with potential implications by microRNA-146aAnti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse modelQuantification of CD4(+) T Cell Alloreactivity and Its Control by Regulatory T Cells Using Time-Lapse Microscopy and Immune Synapse Detection.Differential sensitivity of regulatory and effector T cells to cell death: a prerequisite for transplant tolerance.CD28 Costimulation: From Mechanism to Therapy.Hormonal Modulation of Dendritic Cells Differentiation, Maturation and Function: Implications for the Initiation and Progress of Systemic Autoimmunity.TCR signalling network organization at the immunological synapses of murine regulatory T cells.Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent ActivationCD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity.Host-Directed Therapeutic Strategies for Tuberculosis.First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28.Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses.FR104, an antagonist anti-CD28 monovalent fab' antibody, prevents alloimmunization and allows calcineurin inhibitor minimization in nonhuman primate renal allograft.T Cell Calcium Signaling Regulation by the Co-Receptor CD5.CD28 between tolerance and autoimmunity: the side effects of animal models.CTLA‑4 interferes with the HBV‑specific T cell immune response (Review).CD28 blockade controls T cell activation to prevent graft-versus-host disease in primatesClinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis
P2860
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P2860
Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@ast
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@en
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@nl
type
label
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@ast
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@en
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@nl
prefLabel
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@ast
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@en
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@nl
P2093
P2860
P1433
P1476
Targeting CD28, CTLA-4 and PD- ...... atory and conventional T-cells
@en
P2093
Béatrice Clémenceau
Caroline Mary
Flora Coulon
Gilles Blancho
Nahzli Dilek
Nicolas Poirier
Philippe Hulin
Simon Ville
P2860
P304
P356
10.1371/JOURNAL.PONE.0083139
P407
P577
2013-01-01T00:00:00Z